Evidence map›Paper›PMID 36317160›Full record

ArticleiScience2022

Mechanical guidance of self-condensation patterns of differentiating progeny.

Takahisa Matsuzaki, Yuko Shimokawa, Hiroyuki Koike, Masaki Kimura, Yuma Kawano, Nao Okuma, Ryuzo Kawamura, Yosuke Yoneyama, Yasuro Furuichi, Fumihiko Hakuno and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 2 countries.

Takahisa MatsuzakiCenter for Future Innovation, Graduate School of Engineering, Osaka University, 2-1, Yamadaoka, Suita, Osaka 565-0871, Japan.
Yuko ShimokawaDepartment of Chemistry, Saitama University, Shimo-okubo 255, Sakura-ku, Saitama 338-8570, Japan.
Hiroyuki KoikeDepartment of Pediatrics, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229- 3039, USA.
Masaki KimuraDepartment of Pediatrics, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229- 3039, USA.
Yuma KawanoDepartment of Chemistry, Saitama University, Shimo-okubo 255, Sakura-ku, Saitama 338-8570, Japan.
Nao OkumaDepartment of Chemistry, Saitama University, Shimo-okubo 255, Sakura-ku, Saitama 338-8570, Japan.
Ryuzo KawamuraDepartment of Chemistry, Saitama University, Shimo-okubo 255, Sakura-ku, Saitama 338-8570, Japan.
Yosuke YoneyamaInstitute of Research, Division of Advanced Multidisciplinary Research, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo 113-8510, Japan.
Yasuro FuruichiDepartment of Health Promotion Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, Tokyo, Japan.
Fumihiko HakunoDepartments of Animal Sciences and Applied Biological Chemistry, Graduate School of Agriculture and Life Sciences, the University of Tokyo, Bunkyo-Ku, Tokyo 113-8657, Japan.
Shin-Ichiro TakahashiDepartments of Animal Sciences and Applied Biological Chemistry, Graduate School of Agriculture and Life Sciences, the University of Tokyo, Bunkyo-Ku, Tokyo 113-8657, Japan.
Seiichiro NakabayashiDivision of Strategic Research and Development, Graduate School of Science and Engineering, Saitama University, Shimo-Okubo 255, Sakura-Ku, Saitama 338-8570, Japan.
Satoshi OkamotoDepartment of Regenerative Medicine, Graduate School of Medicine, Yokohama City University, Kanazawa-Ku 3-9, Yokohama, Kanagawa, 236-0004, Japan.
Hiromitsu NakauchiInstitute for Stem Cell Biology and Regenerative Medicine, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Hideki TaniguchiDepartment of Regenerative Medicine, Graduate School of Medicine, Yokohama City University, Kanazawa-Ku 3-9, Yokohama, Kanagawa, 236-0004, Japan.
Takanori TakebeDepartment of Pediatrics, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229- 3039, USA.
Hiroshi Y YoshikawaDepartment of Applied Physics, Graduate School of Engineering, Osaka University, 2-1, Yamadaoka, Suita, Osaka 565-0871, Japan.
Saitama University · JPThe University of Tokyo · JPCincinnati Children's Hospital Medical Center · USOsaka University · JPTokyo University of Science · JPTokyo Metropolitan University · JPUniversity of Cincinnati Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spatially controlled self-organization represents a major challenge for organoid engineering. We have developed a mechanically patterned hydrogel for controlling self-condensation process to generate multi-cellular organoids. We first found that local stiffening with intrinsic mechanical gradient (

Indexed as

BiomaterialsBiomechanical engineeringMechanobiology

Identifiers

PMID36317160
PMCPMC9617469
OpenAlexW4297322775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.