Evidence map›Paper›PMID 36317156›Full record

ArticleCase reports in pulmonology2022

Alveolar Proteinosis in COVID-19: Clinical Case.

Silvia Martin Bote, Maria Angeles Herrera Morueco, Beatriz Arias Arcos, Javier García Lopez, Maria Belen Lopez-Muñiz Ballesteros

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in pulmonology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Silvia Martin BoteDepartment of Respiratory Medicine, Infanta Leonor University Hospital, Madrid, Spain.ORCID https://orcid.org/0000-0001-7656-2542
Maria Angeles Herrera MoruecoDepartment of Internal Medicine, Infanta Leonor University Hospital, Madrid, Spain.ORCID https://orcid.org/0000-0002-7204-6222
Beatriz Arias ArcosDepartment of Respiratory Medicine, Infanta Leonor University Hospital, Madrid, Spain.ORCID https://orcid.org/0000-0001-5799-9255
Javier García LopezDepartment of Respiratory Medicine, Gregorio Marañón General University Hospital, Madrid, Spain.ORCID https://orcid.org/0000-0002-4387-4221
Maria Belen Lopez-Muñiz BallesterosDepartment of Respiratory Medicine, Infanta Leonor University Hospital, Madrid, Spain.
Hospital Universitario Infanta Leonor · ESHospital General Universitario Gregorio Marañón · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary alveolar proteinosis (PAP) is a rare, diffuse lung disease characterized by accumulation of lipoprotein in lung surfactant in the alveolar space and terminal bronchioles, leading to impaired gas exchange and arterial hypoxemia. We present the case of a 51-year-old woman who was admitted with a diagnosis of severe SARS-CoV-2 pneumonia. Her condition did not improve with corticosteroids. A chest CT scan revealed ground-glass opacities in all lung lobes, with septal thickening. A differential diagnosis was proposed with other diseases. Bronchoscopy revealed milky bronchoalveolar lavage fluid, and staining with periodic acid-Schiff was positive, thus indicating PAP. Therefore, the patient underwent whole lung lavage, which led to clinical, radiological, and functional improvement. In the context of the COVID-19 pandemic, differential diagnosis ensures that appropriate attention is given to less prevalent entities such as PAP.

Identifiers

PMID36317156
PMCPMC9617725
OpenAlexW4307136624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.