Evidence map›Paper›PMID 36317015›Full record

ReviewAdvances in pharmacological and pharmaceutical sciences2022

Current Trends on Solid Dispersions: Past, Present, and Future.

Ruba Malkawi, Walla I Malkawi, Yahia Al-Mahmoud, Jawad Tawalbeh

Abstract readReview
In one paragraph

Review in Advances in pharmacological and pharmaceutical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
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  3. Review
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  6. Advances in Drug Delivery Systems for Boswellic Acids fromInternational journal of molecular sciences · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Frontiers in molecular biosciences · 2026
    Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ruba MalkawiSchool of Pharmacy, Jadara University, P.O. Box 733, Irbid 21110, Jordan.ORCID https://orcid.org/0000-0001-9025-6752
Walla I MalkawiSchool of Pharmacy, Iowa State University, Ames, IA 50011, USA.
Yahia Al-MahmoudSchool of Pharmacy, Jadara University, P.O. Box 733, Irbid 21110, Jordan.
Jawad TawalbehSchool of Business, Teesside University, Campus Heart, Southfield Rd, Middlesbrough TS1 3BX, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Solid dispersions have achieved significant interest as an effective means of enhancing the dissolution rate and thus the bioavailability of a range of weakly water-soluble drugs. Solid dispersions of weakly water-soluble drugs with water-soluble carriers have lowered the frequency of these problems and improved dissolution. Solid dispersion is a solubilization technology emphasizing mainly on, drug-polymer two-component systems in which drug dispersion and its stabilization is the key to formulation development. Therefore, this technology is recognized as an exceptionally useful means of improving the dissolution properties of poorly water-soluble drugs and in the latest years, a big deal of understanding has been accumulated about solid dispersion, however, their commercial application is limited. In this review article, emphasis is placed on solubility, BCS classification, and carriers. Moreover, this article presents the diverse preparation techniques for solid dispersion and gathers some of the recent technological transfers. The different types of solid dispersions based on the carrier used and molecular arrangement were underlined. Additionally, it summarizes the mechanisms, the methods of preparing solid dispersions, and the marketed drugs that are available using solid dispersion approaches.

Identifiers

PMID36317015
PMCPMC9617737

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.