Evidence map›Paper›PMID 36316771›Full record

ArticleBMC cancer2022

A predictive model based on site-specific risk factors of recurrence regions in endometrial cancer patients.

Wonkyo Shin, Seong J Yang, Sang-Yoon Park, Sokbom Kang, Dong Ock Lee, Myong Cheol Lim, Sang-Soo Seo

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Wonkyo Shin *Center for Gynecologic Cancer, National Cancer Center, Goyang, Republic of Korea.ORCID http://orcid.org/0000-0002-5728-250X
Seong J Yang *Department of Statistics (Institute of Applied Statistics), Jeonbuk National University, Jeonju, Republic of Korea.ORCID http://orcid.org/0000-0002-6738-1181
Sang-Yoon ParkCenter for Gynecologic Cancer, National Cancer Center, Goyang, Republic of Korea.ORCID http://orcid.org/0000-0001-8325-6009
Sokbom KangCenter for Gynecologic Cancer, National Cancer Center, Goyang, Republic of Korea.ORCID http://orcid.org/0000-0002-8428-9555
Dong Ock LeeCenter for Gynecologic Cancer, National Cancer Center, Goyang, Republic of Korea.ORCID http://orcid.org/0000-0002-9009-3508
Myong Cheol LimCenter for Gynecologic Cancer, National Cancer Center, Goyang, Republic of Korea.ORCID http://orcid.org/0000-0001-8964-7158
Sang-Soo SeoCenter for Gynecologic Cancer, National Cancer Center, Goyang, Republic of Korea. ssseomd@ncc.re.kr.ORCID http://orcid.org/0000-0003-2381-0965
National Cancer Center · KRChungnam National University · KRJeonbuk National University · KRNational Cancer Center · US

Funding

National Cancer Center NCC-1910180
6 · The paper itself

Abstract

objectiveThis study investigated site-specific differences in clinical factors for recurrence in patients who were newly diagnosed and treated for endometrial cancer. A model for predicting recurrence sites was generated.

methodsElectronic medical records' data were retrieved from January 2006 to December 2018 for patients who were diagnosed with endometrial cancer at the National cancer center in Korea. Recurrence sites were classified as local, regional, or distant. We used multinomial logistic regression models that modeled the log-odds for the three recurrence sites relative to non-recurrence as a linear combination of possible risk factors for the recurrence of endometrial cancer.

resultsThe data of 611 patients were selected for analysis; there were 20, 12, and 25 cases of local, regional, and distant recurrence, respectively, and 554 patients had no recurrence. High-grade disease was associated with local recurrence; non-endometrioid histology and parametrial invasion were risk factors for regional recurrence; additionally, parametrial invasion and no lymphadenectomy were associated with distant metastasis.

conclusionWe identified different risk factors specific for each type of recurrence site. Using these risk factors, we suggest that individually tailored adjuvant treatments be introduced for patients.

Indexed as

Endometrial NeoplasmsNeoplasm Recurrence, LocalFemaleHumansLymph Node ExcisionNeoplasm StagingRetrospective StudiesRisk FactorsEndometrial cancerLymph nodeLymph node dissectionSurvival rate

Identifiers

PMID36316771
PMCPMC9620664
OpenAlexW4307885317

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.