Evidence map›Paper›PMID 36316617›Full record

Trial reportInternational journal of implant dentistry2022

Clinical applications of concentrated growth factors membrane for sealing the socket in alveolar ridge preservation: a randomized controlled trial.

Yumeng Liu, Xiaoming Li, Changwei Jiang, Huiying Guo, Guisheng Luo, Yangyang Huang, Changyong Yuan

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of implant dentistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yumeng LiuSchool of Stomatology, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Xiaoming LiDepartment of Oral Implantology, The Affiliated Stomatological Hospital of Xuzhou Medical University, 130 Huaihai West Road, Xuzhou, 221000, Jiangsu, China.
Changwei JiangDepartment of Oral Implantology, The Affiliated Stomatological Hospital of Xuzhou Medical University, 130 Huaihai West Road, Xuzhou, 221000, Jiangsu, China.
Huiying GuoSchool of Stomatology, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Guisheng LuoSchool of Stomatology, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Yangyang HuangSchool of Stomatology, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Changyong YuanDepartment of Oral Implantology, The Affiliated Stomatological Hospital of Xuzhou Medical University, 130 Huaihai West Road, Xuzhou, 221000, Jiangsu, China. yuanchangyong1983@foxmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to evaluate the efficacy of concentrated growth factor (CGF) membrane for the sealing of alveolar socket in alveolar ridge preservation (ARP). A total of 22 patients with 24 alveolar sockets were recruited and divided randomly into CGF group and Bio-Gide collagen membrane group. The soft tissue wound healing rate was calculated using intraoral scanner at 3, 7, and 14 days after ARP, and the bone resorption volume at 1, 3, and 5 mm below the alveolar ridge was measured by CBCT at 6 months postoperation. The keratinized gingival width was also measured before and 6 months after ridge preservation. In terms of soft tissue healing rate, the CGF group exhibited significant higher than that of Bio-Gide group at both 7 and 14 days after surgery (P < 0.05). However, there was no significantly different in bone resorption rate and the width of keratinized gingival after 6 months (P > 0.05). Therefore, the use of CGFs membranes for wound closure in ARP is a reliable method, but more clinical data are needed to prove it.

Indexed as

Alveolar Ridge AugmentationBone ResorptionAlveolar ProcessHumansIntercellular Signaling Peptides and ProteinsTooth ExtractionTooth SocketIntercellular Signaling Peptides and ProteinsAlveolar ridge preservationConcentration growth factorsDental implantSoft tissue healing

Identifiers

PMID36316617
PMCPMC9622971

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.