Evidence map›Paper›PMID 36316522›Full record

ArticleScientific reports2022

Quality and safety investigation of commonly used topical cosmetic preparations.

May Almukainzi, Lubna Alotaibi, Anfal Abdulwahab, Nada Albukhary, Areej M El Mahdy

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Study of contaminants in natural cosmetics.International journal of occupational medicine and environmental health · 2026
    Article
  4. Article
  5. Article
  6. Skin Whitening Creams: Cosmetovigilance.Current pharmaceutical biotechnology · 2026
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Contamination and Carcinogenic Risks of Lead in Lip Cosmetics in China.Bulletin of environmental contamination and toxicology · 2024
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

May AlmukainziDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671, Saudi Arabia. mkalmukainizi@pnu.edu.sa.
Lubna AlotaibiCollege of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Anfal AbdulwahabCollege of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Nada AlbukharyCollege of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Areej M El MahdyDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671, Saudi Arabia.
Princess Nourah bint Abdulrahman University · SAMansoura University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cosmetic and personal care products are considered an essential part of our daily care routine; hence, these products must be stable and safe for human use. This study aimed to assess the quality and safety of the most common cosmetic preparations. To select the products to be tested, a cross-sectional survey was distributed featuring the most used types and brands of products. Based on 447 responses from both males and females with different ages and education levels, 21 products from different brands were selected and tested in terms of microbial load, heavy metal content, and organoleptic properties. Microbial contamination was investigated using the aerobic plate count method. Lead (Pb), aluminum (Al), cadmium (Cd), cobalt (Co), chromium (Cr), copper (Cu), manganese (Mn), nickel (Ni), zinc (Zn), iron (Fe), and arsenic (As) impurities were analyzed using an inductively coupled plasma mass spectrometer. The products included sunblock, lip balm, hand cream, hair cream, shampoo, cleanser, baby oil, baby powder, bar soap, hair dye, makeup, deodorant, hair serum, shaving gel, and toothpaste. Microbial contamination was found in 14 of the products, ranging between 1467.5 and 299.5 cfu/ml. The most commonly isolated microorganisms were Staphylococcus aureus and Bacillus species. Most of the tested products showed metal impurities, with toothpaste having the highest concentrations of Pb, Cr, As, Cu and Ni. The samples did not show lumps or discoloration, did not have characteristic odors, and had pH values ranging from 6.90 to 8.10. The continuous usage of such products could lead to serious negative consequences. As a result, ensuring the quality of cosmetic products is critical. Regulatory authorities are required to enforce strict legislation on cosmetic manufacturing to assess and ensure the quality and safety of the products before they reach consumers.

Indexed as

ArsenicCosmeticsMetals, HeavyCadmiumChromiumCross-Sectional StudiesEnvironmental MonitoringFemaleHumansLeadMaleNickelToothpastesArsenicCadmiumChromiumCosmeticsLeadMetals, HeavyNickelToothpastes

Identifiers

PMID36316522
PMCPMC9622732
OpenAlexW4307897291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.