Evidence map›Paper›PMID 36316521›Full record

ArticleAAPS PharmSciTech2022

Magnetic Targeting of 5-Fluorouracil-Loaded Liposome-Nanogels for In Vivo Breast Cancer Therapy and the Cytotoxic Effects on Liver and Kidney.

Damla Ulker, Rumeysa Ozyurt, Nilufer Erkasap, Vural Butun

Abstract read
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In one paragraph

Article in AAPS PharmSciTech, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Damla UlkerDepartment of Pharmaceutical Basic Science, Faculty of Pharmacy, Near East University, 99138, Nicosia, Northern Cyprus, Mersin 10, Turkey.
Rumeysa OzyurtDepartment of Physiology, Faculty of Medicine, Kutahya Health Sciences University, 43100, Kutahya, Turkey.
Nilufer ErkasapDepartment of Physiology, Faculty of Medicine, Eskisehir Osmangazi University, 26480, Eskisehir, Turkey.
Vural ButunDepartment of Chemistry, Faculty of Science, Eskisehir Osmangazi University, 26480, Eskisehir, Turkey. vbutun@ogu.edu.tr.
Eskişehir Osmangazi University · TRKutahya Saglik Bilimleri UniversitesiNear East University · CY

Funding

Eskişehir Osmangazi Üniversitesi 201619C104Eskişehir Osmangazi Üniversitesi 201719D05Türkiye Bilimsel ve Teknolojik Araştirma Kurumu 115Z726Türkiye Bilimsel ve Teknolojik Araştirma Kurumu 1649B03140610 - 2211/C
6 · The paper itself

Abstract

In our previous paper, we demonstrated the ex vivo studies of non-toxic liposome-nanogel systems by which the long-term drug release could be provided from hybrid systems for the 5-fluorouracil (5-FU) drug molecule. The aim of this study was the in vivo magnetic targeting of 5-FU-loaded Fe

Indexed as

Antineoplastic AgentsNanoparticlesAnimalsCaspase 3Caspase 9Cell Line, TumorDrug CarriersDrug Delivery SystemsFluorouracilKidneyLiposomesLiverMagnetic PhenomenaMiceNanogelsPolyethylene GlycolsAntineoplastic AgentsCaspase 3Caspase 9Drug CarriersFluorouracilLiposomesNanogelspolyethylene glycol polyethyleneimine nanogelPolyethylene GlycolsPolyethyleneimineRNA, MessengerTumor Suppressor Protein p53breast cancercontrolled drug deliverycytotoxicityliposomemagnetic carriersmagnetic targeting

Identifiers

PMID36316521
OpenAlexW4307882828

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.