Evidence map›Paper›PMID 36316480›Full record

ArticleNature immunology2022

Heterogeneous plasma cells and long-lived subsets in response to immunization, autoantigen and microbiota.

Xin Liu, Jiacheng Yao, Yongshan Zhao, Jianbin Wang, Hai Qi

Erratum issuedOpen access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Nature immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 102 citations in OpenAlex.

  1. Article
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  17. iScience · 2025
    Article
  18. Article
  19. Distinct autoreactive CD19Nature communications · 2025
    Article
  20. Cxcl9Communications biology · 2025
    Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Xin Liu *Tsinghua-Peking Center for Life Sciences, Beijing, China.ORCID http://orcid.org/0000-0002-6634-4012
Jiacheng Yao *College of Chemistry and Molecular Engineering, Peking University, Beijing, China.ORCID http://orcid.org/0000-0002-5212-7527
Yongshan ZhaoTsinghua-Peking Center for Life Sciences, Beijing, China.
Jianbin WangChangping Laboratory, Beijing, China. jianbinwang@tsinghua.edu.cn.ORCID http://orcid.org/0000-0001-6725-7925
Hai QiTsinghua-Peking Center for Life Sciences, Beijing, China. qihai@tsinghua.edu.cn.ORCID http://orcid.org/0000-0001-5475-3989
Center for Life Sciences · CNBeijing Tsinghua Chang Gung Hospital · CNKing Center · USPeking University · CN

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

Durable antibody immunity depends on long-lived plasma cells (LLPCs) that primarily reside in the bone marrow (BM). However, due to LLPC rarity, it has not been possible to define their phenotypes or determine their heterogeneity. By single-cell mRNA sequencing, cytometry and a genetic pulse-chase mouse model, we show that IgG and IgM LLPCs display an EpCAM

Indexed as

MicrobiotaPlasma CellsAnimalsAutoantigensImmunizationImmunoglobulin AImmunoglobulin GImmunoglobulin MMiceAutoantigensImmunoglobulin AImmunoglobulin GImmunoglobulin M

Identifiers

PMID36316480
OpenAlexW4307716772

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.