Evidence map›Paper›PMID 36316143›Full record

ArticleGlobal health, science and practice2022

Community Health Workers Improve HIV Disclosure Among HIV-Affected Sexual Partners in Rural Uganda: A Quasi-Experimental Study.

Zubair Lukyamuzi, Ruth Mirembe Nabisere, Rita Nakalega, Patience Atuhaire, Hajira Kataike, Bashir Ssuna, Mazen Baroudi, Flavia Matovu Kiweewa, Philippa Musoke, Lisa M Butler

Open access · diamondAbstract read
In one paragraph

Article in Global health, science and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Zubair LukyamuziMakerere University-Johns Hopkins University Research Collaboration, Kampala, Uganda. zlukyamuzi@mujhu.org.
Ruth Mirembe NabisereInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Rita NakalegaMakerere University-Johns Hopkins University Research Collaboration, Kampala, Uganda.
Patience AtuhaireMakerere University-Johns Hopkins University Research Collaboration, Kampala, Uganda.
Hajira KataikeMakerere University-Johns Hopkins University Research Collaboration, Kampala, Uganda.
Bashir SsunaUganda Tuberculosis Implementation Research Consortium, Kampala, Uganda.
Mazen BaroudiDepartment of Epidemiology and Global Health, Umeå University, Umeå, Sweden.
Flavia Matovu KiweewaMakerere University-Johns Hopkins University Research Collaboration, Kampala, Uganda.
Philippa MusokeMakerere University-Johns Hopkins University Research Collaboration, Kampala, Uganda.
Lisa M ButlerInstitute for Collaboration on Health, Intervention, and Policy, University of Connecticut, Storrs, CT, USA.
MUJHU Research Collaboration · UGMakerere University · UGUganda Virus Research Institute · UGUmeå University · SEUniversity of Connecticut · US

Funding

UJMT – ORWH – Gazzetta, Issa-BoubeD43TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI William Checkley, Benjamin H. Chi · 2017 to 2026
$14.8M
A Novel Video-Based Intervention to Enhance Optimal Uptake of Malaria Preventive Therapy: A Pilot Study of a Health Educational Approach to Malaria Prevention during PregnancyR03HD106185 · NICHD · MU-JHU CARE · PI NAKALEGA, RITA · 2022 to 2023
$108k
FIC NIH HHS D43 TW009340NICHD NIH HHS R03 HD106185
6 · The paper itself

Abstract

backgroundWe evaluated the efficacy of a community health worker (CHW)-led intervention in supporting disclosure among adults living with HIV in heterosexual relationships.

methodsWe conducted a quasi-experimental study with 2 arms allocated by geographically determined clusters and adjusted for between-group differences among adults living with HIV in the greater Luwero region of Uganda who had never disclosed their status to their current primary sexual partners. Clusters were allocated to either a CHW-led intervention or a control arm. In both arms, participants were consecutively recruited. As opposed to receiving routine care for the control arm, participants in the intervention arm received additional CHW disclosure support. The overall follow-up was 6 months, and the primary outcome was disclosure to the sexual partner. Data were analyzed using a clustered modified Poisson regression model with robust standard errors to determine independent factors associated with disclosure.

resultsOf the 245 participants who enrolled, 230 (93.9%) completed the study, and 112 (48.7%) of those were in the intervention arm. The median age was 30 (interquartile range=25-37) years, the majority were women (76.5%), and most (80%) did not know their partners' HIV status at study entry. At the end of follow-up, the overall disclosure prevalence was 74.4% (95% confidence interval [CI]=68.2, 79.9) and participants in the intervention arm were 51% more likely to disclose compared to those in the control (adjusted relative ratio [aRR]=1.51; 95% CI=1.28, 1.77). Men were 24% (aRR=1.24; 95% CI=1.07, 1.44) more likely to disclose compared to women, and membership in an HIV/AIDS association increased disclosure by 18% (aRR=1.18; 95% CI=1.01, 1.39).

conclusionCHW support improved disclosure among adults living with HIV in heterosexual relationships when compared to routine care. Therefore, CHW-led mechanisms may be utilized in increasing disclosure among adults living with HIV in heterosexual relationships in rural settings.

Indexed as

HIV InfectionsSexual PartnersAdultCommunity Health WorkersDisclosureFemaleHumansMaleUganda

Identifiers

PMID36316143
PMCPMC9622292
OpenAlexW4296688990

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.