Evidence map›Paper›PMID 36316015›Full record

ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2023

Social determinants of health and the transition from advanced chronic kidney disease to kidney failure.

Gregory L Hundemer, Pietro Ravani, Manish M Sood, Deborah Zimmerman, Amber O Molnar, Danielle Moorman, Matthew J Oliver, Christine White, Swapnil Hiremath, Ayub Akbari

Open access · greenAbstract read
In one paragraph

Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

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  4. Social determinants of health and stroke risk: A dose-response analysis of cumulative socioeconomic burden in US adults.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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  9. Interaction BetweenKidney international reports · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Gregory L HundemerDivision of Nephrology, Department of Medicine, University of Ottawa, Ottawa, ON, Canada.ORCID 0000-0003-3559-3531
Pietro RavaniDivision of Nephrology, Department of Medicine, University of Calgary, Calgary, AB, Canada.
Manish M SoodDivision of Nephrology, Department of Medicine, University of Ottawa, Ottawa, ON, Canada.
Deborah ZimmermanDivision of Nephrology, Department of Medicine, University of Ottawa, Ottawa, ON, Canada.ORCID 0000-0003-0000-8806
Amber O MolnarDivision of Nephrology, Department of Medicine, McMaster University, Hamilton, ON, Canada.
Danielle MoormanDivision of Nephrology, Department of Medicine, University of Ottawa, Ottawa, ON, Canada.
Matthew J OliverDivision of Nephrology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
Christine WhiteDivision of Nephrology, Department of Medicine, Queen's University, Kingston, ON, Canada.
Swapnil HiremathDivision of Nephrology, Department of Medicine, University of Ottawa, Ottawa, ON, Canada.ORCID 0000-0003-0010-3416
Ayub AkbariDivision of Nephrology, Department of Medicine, University of Ottawa, Ottawa, ON, Canada.
University of Ottawa · CAMcMaster University · CAQueen's University · CASunnybrook Health Science Centre · CAUniversity of Calgary · CA

Funding

CIHR PJT-183840
6 · The paper itself

Abstract

backgroundThe transition from chronic kidney disease (CKD) to kidney failure is a vulnerable time for patients, with suboptimal transitions associated with increased morbidity and mortality. Whether social determinants of health are associated with suboptimal transitions is not well understood.

methodsThis retrospective cohort study included 1070 patients with advanced CKD who were referred to the Ottawa Hospital Multi-Care Kidney Clinic and developed kidney failure (dialysis or kidney transplantation) between 2010 and 2021. Social determinant information, including education level, employment status and marital status, was collected under routine clinic protocol. Outcomes surrounding suboptimal transition included inpatient (versus outpatient) dialysis starts, pre-emptive (versus delayed) access creation and pre-emptive kidney transplantation. We examined the association between social determinants of health and suboptimal transition outcomes using multivariable logistic regression.

resultsThe mean age and estimated glomerular filtration rate were 63 years and 18 ml/min/1.73 m2, respectively. Not having a high school degree was associated with higher odds for an inpatient dialysis start compared with having a college degree {odds ratio [OR] 1.71 [95% confidence interval (CI) 1.09-2.69]}. Unemployment was associated with higher odds for an inpatient dialysis start [OR 1.85 (95% CI 1.18-2.92)], lower odds for pre-emptive access creation [OR 0.53 (95% CI 0.34-0.82)] and lower odds for pre-emptive kidney transplantation [OR 0.48 (95% CI 0.24-0.96)] compared with active employment. Being single was associated with higher odds for an inpatient dialysis start [OR 1.44 (95% CI 1.07-1.93)] and lower odds for pre-emptive access creation [OR 0.67 (95% CI 0.50-0.89)] compared with being married.

conclusionsSocial determinants of health, including education, employment and marital status, are associated with suboptimal transitions from CKD to kidney failure.

Indexed as

Kidney Failure, ChronicRenal Insufficiency, ChronicHumansRenal DialysisRetrospective StudiesSocial Determinants of Healthchronic kidney disease (CKD)end-stage kidney disease (ESKD)kidney failuresocial determinants of healthtransition

Identifiers

PMID36316015
PMCPMC10310519
OpenAlexW4307751560

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.