Evidence map›Paper›PMID 36315507›Full record

Trial reportPloS one2022

Patients' knowledge about medicines improves when provided with written compared to verbal information in their native language.

Rameshkumar T, Haputhanthrige I U, Misbahunnisa M Y, Galappatthy P

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rameshkumar TDepartment of Pharmacology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.ORCID 0000-0003-0852-0089
Haputhanthrige I UDepartment of Pharmacology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Misbahunnisa M YSchool of Pharmacy, National Hospital of Sri Lanka, Colombo, Sri Lanka.
Galappatthy PDepartment of Pharmacology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
University of Colombo · LKNational Hospital of Sri Lanka · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatient's knowledge on the medicines prescribed is vital in reducing medication errors and improving adherence and patient satisfaction. This study assessed the patients' knowledge on medicines prescribed and compared improvement following verbal or written information given in patients own language.

methodsSeventy-five trainee pharmacists randomised to verbal or written groups, provided information to consecutive consenting patients attending medical and surgical clinics in the outpatient department of National Hospital of Sri Lanka. Baseline knowledge and immediate recall knowledge was scored on 5 categories (name, indication, dose, frequency of administration, and additional relevant details) for each drug prescribed. Scores <5/10, 5-7/10 and > 7/10 were considered as poor, moderate, and good knowledge. Sample of 384 in each group had 80% power to detect a 10% difference in knowledge level. Data was analysed using SPSS v26.

resultsOf the 747 patients, 429(57%) were females, mean age was 54.3 years(SD±12), 450(60%) were on 5 or more drugs and 149(20%) were elderly (>65 years). At baseline, knowledge scores were comparable in both groups with 47% (352/747) patients having poor knowledge, 34% (254/747) moderate knowledge and only 19% (141/747) good knowledge. Patients knew the name only on 1653(42%) drugs prescribed, indication on 1603(41%), dose on 860(22%), administration details on 2255(58%) and additional details (adverse effects/storage) only on 267(7%) medicines prescribed. After the intervention, 276(74%) patients had good knowledge (score>7), in written group vs 217(58%) in verbal group (p<0.05). In all 5 aspects knowledge improved significantly more in written group compared to the verbal group. Binomial logistic regression analysis indicated that ordinary level (OR:2.32), advanced level(OR:2.13) and university education(OR:3.72), and lower number of medicines prescribed(OR:0.83) significantly increased the odds of having a "Good Knowledge on Medicines".

conclusionPatient's knowledge on medicines prescribed was poor and providing the medication plan in writing in patients' own language would improve the knowledge significantly compared to providing verbal information.

Indexed as

LanguagePatient SatisfactionAgedFemaleHumansMaleMiddle AgedPharmacistsSri LankaWriting

Identifiers

PMID36315507
PMCPMC9621412
OpenAlexW4307715249

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.