Evidence map›Paper›PMID 36315439›Full record

ArticlePopulation health management2022

Global Challenges with Oral Antivirals for COVID-19.

Dallas J Smith, Avi J Hakim, Andrea Taylor, Sarah D Bennett, Pragna Patel, Ashley Greiner, Barbara J Marston

Open access · hybridAbstract read
In one paragraph

Article in Population health management, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Disparities in COVID-19 clinical studies from high-income and low-and middle-income countries.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Dallas J SmithEpidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID 0000-0001-5707-528X
Avi J HakimCOVID-19 Response International Task Force, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Andrea TaylorDuke Global Health Innovation Center, Duke Global Health Institute, Duke University, Durham, North Carolina, USA.
Sarah D BennettEpidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Pragna PatelEpidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Ashley GreinerEpidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Barbara J MarstonEpidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Centers for Disease Control and Prevention · USDuke University · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Oral antivirals for COVID-19 can be game changers in low- and middle-income countries (LMICs). Challenges that may hinder current and future oral antiviral rollouts span use in special populations, drug-drug and herb-drug interactions, adverse events, development of resistance, black markets, and equity in access and prescribing. Future antivirals may address some of these barriers; however, health systems around the world should be equipped to receive and administer COVID-19 oral antivirals. Improvements in manufacturing capacity, community engagement, capacity for testing and linkage to care, and systems for surveillance and safety monitoring could "change the game" for LMICs, irrespective of any specific antiviral drug. Investments in health care infrastructure can promote resilience, not only for COVID-19 but also for future local and global health crises.

Indexed as

COVID-19Antiviral AgentsDeveloping CountriesGlobal HealthHumansAntiviral AgentsantiviralsCOVID-19global healthhealth care infrastructure

Identifiers

PMID36315439
PMCPMC10894658
OpenAlexW4307776068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.