Evidence map›Paper›PMID 36315322›Full record

ArticleJournal of autism and developmental disorders2024

Associations Among Sex, Cognitive Ability, and Autism Symptoms in Individuals with Down Syndrome.

Laura Del Hoyo Soriano, Audra Sterling, Jamie Edgin, Debra R Hamilton, Elizabeth Berry-Kravis, Amanda Dimachkie Nunnally, Angela John Thurman, Leonard Abbeduto

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Laura Del Hoyo SorianoMIND Institute, University of California Davis, 2825 50th Street, Sacramento, CA, USA. ldelhoyo@ucdavis.edu.ORCID http://orcid.org/0000-0003-4372-1599
Audra SterlingWaisman Center, Department of Communication Sciences and Disorders, University of Wisconsin-Madison, Madison, WI, USA.
Jamie EdginDepartment of Psychology, University of Arizona, Tucson, AZ, USA.
Debra R HamiltonDepartment of Human Genetics, School of Medicine, Emory University, Atlanta, GA, USA.
Elizabeth Berry-KravisDepartments of Pediatrics, Neurological Sciences and Biochemistry, Rush University Medical Center, Chicago, USA.
Amanda Dimachkie NunnallyMIND Institute, University of California Davis, 2825 50th Street, Sacramento, CA, USA.
Angela John ThurmanMIND Institute, University of California Davis, 2825 50th Street, Sacramento, CA, USA.
Leonard AbbedutoMIND Institute, University of California Davis, 2825 50th Street, Sacramento, CA, USA.
University of California Davis Medical Center · USEmory University · USRush University Medical Center · USUniversity of Arizona · USUniversity of California System · USUniversity of Wisconsin–Madison · US

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
Research Project: Pathologic Significance of Maternal AutoantibodiesP50HD103526 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEONARD J. ABBEDUTO, Melissa Dawn Bauman · 2020 to 2026
$9.7M
Interdisciplinary Training for Autism Researchers(RMI)T32MH073124 · NIMH · UNIVERSITY OF CALIFORNIA DAVIS · PI Stephen Charles Noctor, Christine Wu Nordahl · 2004 to 2026
$6.8M
Expressive Language Sampling as an Outcome MeasureR01HD074346 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ABBEDUTO, LEONARD J. · 2013 to 2017
$3.9M
NCATS NIH HHS UL1 TR001860NCATS NIH HHS UL1TR001860NICHD NIH HHS P50 HD103526NICHD NIH HHS R01 HD074346NIMH NIH HHS T32 MH073124
6 · The paper itself

Abstract

This study explores sex-differences in (a) rates and profiles of autism symptoms as well as in (b) the contribution of intellectual quotient (IQ) to autism symptom presentation in Down syndrome (DS). Participants were 40 males and 38 females with DS, aged 6 to 23 years. Autism symptoms were rated through the Autism Diagnostic Observation Schedule-Second Edition (ADOS-2). Results show no sex differences in the ADOS-2 Calibrated Severity Scores (CSS). However, only females with DS who are classified as DS-Only have higher scores on verbal IQ than those classified as DS + autism. Furthermore, associations between IQ and all CSSs are found for females, but not for males. Findings suggest that verbal cognition may play differential roles for females and males with DS.

Indexed as

Autism Spectrum DisorderAutistic DisorderDown SyndromeCognitionFemaleHumansMaleSex CharacteristicsAutismCognitive abilityDown syndromeFemalesSex-differences

Identifiers

PMID36315322
PMCPMC10184887
OpenAlexW4307779272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.