Evidence map›Paper›PMID 36315239›Full record

ReviewJournal of medical Internet research2022

Technical, Ethical, Legal, and Societal Challenges With Digital Twin Systems for the Management of Chronic Diseases in Children and Young People.

David Drummond, Adrien Coulet

Open access · goldAbstract readReview
In one paragraph

Review in Journal of medical Internet research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. A survey on ethical digital twins in healthcare.Frontiers in artificial intelligence · 2026
    Review
  5. Article
  6. Review
  7. Pediatrics 4.0: the Transformative Impacts of the Latest Industrial Revolution on Pediatrics.Health care analysis : HCA : journal of health philosophy and policy · 2025
    Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Digital twins for chronic lung diseases.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  15. Review
  16. Article
  17. Intelligent Digital Twins for Personalized Migraine Care.Journal of personalized medicine · 2023
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

David DrummondDepartment of Paediatric Pulmonology and Allergology, University Hospital Necker-Enfants Malades, AP-HP, Paris, France.ORCID 0000-0002-7324-4992
Adrien CouletHeka Team, Centre de Recherche des Cordeliers, Inserm, Université Paris Cité, Paris, France.ORCID 0000-0002-1466-062X
Hôpital Necker-Enfants Malades · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in digital medicine now make it possible to use digital twin systems (DTS), which combine (1) extensive patient monitoring through the use of multiple sensors and (2) personalized adaptation of patient care through the use of software. After the artificial pancreas system already operational in children with type 1 diabetes, new DTS could be developed for real-time monitoring and management of children with chronic diseases. Just as providing care for children is a specific discipline-pediatrics-because of their particular characteristics and needs, providing digital care for children also presents particular challenges. This article reviews the technical challenges, mainly related to the problem of data collection in children; the ethical challenges, including the need to preserve the child's place in their care when using DTS; the legal challenges and the dual need to guarantee the safety of DTS for children and to ensure their access to DTS; and the societal challenges, including the needs to maintain human contact and trust between the child and the pediatrician and to limit DTS to specific uses to avoid contributing to a surveillance society and, at another level, to climate change. .

Indexed as

Diabetes Mellitus, Type 1TrustAdolescentChildChronic DiseaseFamilyHumansartificial intelligencechildchildrenchronic diseasecyber-physicaldata collectiondigital healthdigital medicinedigital twineHealthethicalethicslawlegalmedical cyber-physical systemsmedical systemmonitorpaediatricpaediatricianpediatricianpediatricspersonalizedprivacysensoryoung peopleyouth

Identifiers

PMID36315239
PMCPMC9664337
OpenAlexW4307877630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.