Evidence map›Paper›PMID 36315028›Full record

ArticleJournal of veterinary internal medicine2022

Natural history of hypertrophic cardiomyopathy in cats from rehoming centers: The CatScan II study.

Jose Novo Matos, Jessie Rose Payne, Joonbum Seo, Virginia Luis Fuentes

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Jose Novo MatosClinical Science and Services, Royal Veterinary College, Hertfordshire, UK.ORCID https://orcid.org/0000-0001-8128-8111
Jessie Rose PayneLangford Vets Small Animal Referral Hospital, University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0001-6057-520X
Joonbum SeoAnimal Referral Centre, Auckland, New Zealand.ORCID https://orcid.org/0000-0002-8215-1237
Virginia Luis FuentesClinical Science and Services, Royal Veterinary College, Hertfordshire, UK.ORCID https://orcid.org/0000-0001-8076-3806
Royal Veterinary College · GBUniversity of Bristol · GBWillows Veterinary Centre and Referral Service · GB

Funding

Everts Luff Feline EndowmentIDEXX LaboratoriesPetplan Charitable Trust
6 · The paper itself

Abstract

backgroundThe natural history of hypertrophic cardiomyopathy (HCM) in cats has been mainly studied in cats referred for suspected heart disease, which can skew the results towards cats with clinical signs. Few data are available on factors associated with development of HCM in cats. HYPOTHESES: (1) Clinical variables can predict which cats will develop HCM; (2) HCM in cats not referred for suspected heart disease is associated with a low rate of cardiovascular events. ANIMALS: One hundred seven cats from rehoming centers without a history of clinical signs of cardiac or systemic disease at the time of adoption.

methodsProspective longitudinal study. After rehoming, shelter cats were reexamined for serial echocardiograms. Cox regression analysis was used to identify predictors of development of HCM in cats that were normal at baseline. Adverse cardiovascular events including heart failure, thromboembolism, or sudden death were recorded.

resultsCats were monitored for a median of 5.6 [1.2-9.2] years. At baseline, 68/107 cats were normal, 18/107 were equivocal and 21/107 had HCM. Nineteen cats developed HCM during the study period. The factors at baseline associated with increased hazard of developing HCM were lower left atrial fractional shortening, higher left ventricular fractional shortening, and higher body weight. Cardiovascular events were observed in 21% of cats with HCM. CONCLUSIONS AND CLINICAL IMPORTANCE: Cardiovascular events were common in cats with HCM from a rehoming center study sample. Lower left atrial systolic function appears to precede overt HCM.

Indexed as

Cardiomyopathy, HypertrophicCat DiseasesAnimalsCatsEchocardiographyHeart AtriaLongitudinal StudiesProspective Studiesdynamic left ventricular outflow tract obstructionleft atrial fractional shorteningleft atrial functionpredictors of HCMshelter catssystolic anterior motion

Identifiers

PMID36315028
PMCPMC9708425
OpenAlexW4307778345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.