Evidence map›Paper›PMID 36314964›Full record

ArticleMicrobiology spectrum2022

The Antibacterial Activity of Kaempferol Combined with Colistin against Colistin-Resistant Gram-Negative Bacteria.

Huijing Zhou, Mengxin Xu, Wenhui Guo, Zhuocheng Yao, Xin Du, Lijiang Chen, Yao Sun, Shiyi Shi, Jianming Cao, Tieli Zhou

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 46 citations in OpenAlex.

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  13. Mechanism of Mongolian Medicine Batri-7 onJournal of inflammation research · 2025
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  14. Nicorandil reduces the antimicrobial effectiveness of polymyxin E againstFrontiers in cellular and infection microbiology · 2025
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  16. Article
  17. Article
  18. Review
  19. The use of combination therapy for the improvement of colistin activity against bacterial biofilm.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Huijing ZhouDepartment of Clinical Laboratory, Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical Universitygrid.268099.c, Wenzhou, China.
Mengxin XuDepartment of Clinical Laboratory, Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical Universitygrid.268099.c, Wenzhou, China.
Wenhui GuoDepartment of Clinical Laboratory, Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical Universitygrid.268099.c, Wenzhou, China.
Zhuocheng YaoDepartment of Medical Laboratory Science, School of Laboratory Medicine and Life Science, Wenzhou Medical Universitygrid.268099.c, Wenzhou, Zhejiang Province, People's Republic of China.
Xin DuDepartment of Clinical Laboratory, Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical Universitygrid.268099.c, Wenzhou, China.
Lijiang ChenDepartment of Clinical Laboratory, Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical Universitygrid.268099.c, Wenzhou, China.
Yao SunDepartment of Clinical Laboratory, Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical Universitygrid.268099.c, Wenzhou, China.
Shiyi ShiDepartment of Clinical Laboratory, Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical Universitygrid.268099.c, Wenzhou, China.
Jianming CaoDepartment of Medical Laboratory Science, School of Laboratory Medicine and Life Science, Wenzhou Medical Universitygrid.268099.c, Wenzhou, Zhejiang Province, People's Republic of China.ORCID 0000-0002-9968-6721
Tieli ZhouDepartment of Clinical Laboratory, Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical Universitygrid.268099.c, Wenzhou, China.ORCID 0000-0002-2171-4710
Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Social hygiene is seriously threatened by the rise in colistin (COL) resistance against Gram-negative bacteria (GNB). With resistance to last-line antibiotics such as COL becoming more common, it is imperative to identify alternative treatment options. In our work, we sought to determine if COL plus kaempferol (KP) present synergistic effects on the antibacterial and antibiofilm activities against colistin-resistant (Col-R) GNB

Indexed as

ColistinGram-Negative Bacterial InfectionsAnti-Bacterial AgentsDrug Resistance, Multiple, BacterialGram-Negative BacteriaHumansKaempferolsMicrobial Sensitivity TestsAnti-Bacterial AgentsColistinKaempferolsbiofilmcolistin-resistanceGram-negative bacteriakaempferolsynergistic effect

Identifiers

PMID36314964
PMCPMC9769984
OpenAlexW4307771168

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.