Evidence map›Paper›PMID 36314849›Full record

ArticleAnnals of medicine2022

Polymorphisms in glucose homeostasis genes are associated with cardiovascular and renal parameters in patients with diabetic nephropathy.

Sonia Mota-Zamorano, Luz M González, Nicolás R Robles, José M Valdivielso, José C Arévalo-Lorido, Juan López-Gómez, Guillermo Gervasini

Open access · goldAbstract read
In one paragraph

Article in Annals of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  3. Association ofDiabetes, metabolic syndrome and obesity : targets and therapy · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Sonia Mota-ZamoranoDepartment of Medical and Surgical Therapeutics, Medical School, Universidad de Extremadura, Badajoz, Spain.
Luz M GonzálezDepartment of Medical and Surgical Therapeutics, Medical School, Universidad de Extremadura, Badajoz, Spain.
Nicolás R RoblesRICORS2040 Renal Research Network, Madrid, Spain.ORCID 0000-0003-4984-6691
José M ValdivielsoRICORS2040 Renal Research Network, Madrid, Spain.ORCID 0000-0003-1343-0184
José C Arévalo-LoridoService of Internal Medicine, Badajoz University Hospital, Badajoz, Spain.ORCID 0000-0002-2654-9339
Juan López-GómezService of Clinical Analyses, Badajoz University Hospital, Badajoz, Spain.
Guillermo GervasiniDepartment of Medical and Surgical Therapeutics, Medical School, Universidad de Extremadura, Badajoz, Spain.ORCID 0000-0002-0524-9767
Spanish Clinical Research Network · ESCentro de Implantología Cirugía Oral y Maxilofacial · ESUniversidad de Extremadura · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetic nephropathy (DN) has become the major cause of end-stage kidney disease and is associated to an extremely high cardiovascular (CV) risk.

methodsWe screened 318 DN patients for 23 SNPs in four glucose transporters (

resultsIn the patient's cohort, common carotid intima media thickness values were higher in carriers of

conclusionsPolymorphisms in genes determining glucose homeostasis may play a relevant role in renal parameters and CV-related outcomes of DN patients.

Indexed as

Diabetes Mellitus, Type 2Diabetic NephropathiesCarotid Intima-Media ThicknessGlomerular Filtration RateGlucoseHomeostasisHumansKidneyPolymorphism, Single NucleotideGlucoseChronic kidney diseasediabetic kidney diseasediabetic nephropathyglucose homeostasistype 2 diabetes mellitus

Identifiers

PMID36314849
PMCPMC9635471
OpenAlexW4307890926

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.