Evidence map›Paper›PMID 36314819›Full record

ArticleJournal of virology2022

WTAP Targets the METTL3 m

Matthew T Sacco, Katherine M Bland, Stacy M Horner

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 42 citations in OpenAlex.

  1. m6A epigenetic modification of viral RNA is critical for the transmission cycle of mosquito-borne flaviviruses.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Targeting G9a-miScience · 2025
    Article
  9. Article
  10. Review
  11. Unveiling the dynamics and therapeutic potential of mInternational journal of biological sciences · 2025
    Review
  12. Review
  13. Recent insights into NCurrent opinion in genetics & development · 2024
    Review
  14. Challenges to mapping and defining mRNA (New York, N.Y.) · 2024
    Article
  15. NNature communications · 2024
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Interconnections between mLife science alliance · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Matthew T SaccoDepartment of Molecular Genetics & Microbiology, Duke Universitygrid.26009.3d School of Medicine, Durham, North Carolina, USA.
Katherine M BlandDepartment of Molecular Genetics & Microbiology, Duke Universitygrid.26009.3d School of Medicine, Durham, North Carolina, USA.
Stacy M HornerDepartment of Molecular Genetics & Microbiology, Duke Universitygrid.26009.3d School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-9351-7409
Duke University · US

Funding

Viral Oncology Training GrantT32CA009111 · NCI · DUKE UNIVERSITY · PI LUFTIG, MICAH A. · 1985 to 2023
$8.9M
Defining the role of the RNA modification N6-methyladenosine in the hepatitis C virus lifecycleR01AI125416 · NIAID · DUKE UNIVERSITY · PI Stacy Michelle Horner · 2016 to 2026
$5.5M
NCI NIH HHS T32 CA009111NIAID NIH HHS R01 AI125416
6 · The paper itself

Abstract

Modification of the hepatitis C virus (HCV) positive-strand RNA genome by N6-methyladenosine (m

Indexed as

Cell Cycle ProteinsHepatitis CMethyltransferasesRNA Splicing FactorsCell NucleusHepacivirusHumansRNA, MessengerRNA, ViralCell Cycle ProteinsMethyltransferasesMETTL3 protein, humanRNA, MessengerRNA Splicing FactorsRNA, ViralWTAP protein, humanHCVMETTL14METTL3N6-methyladenosineRNA modificationWTAP

Identifiers

PMID36314819
PMCPMC9683008
OpenAlexW4307886206

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.