Evidence map›Paper›PMID 36314549›Full record

ReviewJournal of the Pediatric Infectious Diseases Society2022

Social Determinants of Adherence to Treatment for Tuberculosis Infection and Disease Among Children, Adolescents, and Young Adults: A Narrative Review.

Anna M Leddy, Devan Jaganath, Rina Triasih, Eric Wobudeya, Marcia C Bellotti de Oliveira, Yana Sheremeta, Mercedes C Becerra, Silvia S Chiang

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of the Pediatric Infectious Diseases Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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  20. Clinical standards for drug-susceptible TB in children and adolescents.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

Anna M LeddyDivision of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, California, USA.
Devan JaganathDivision of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, California, USA.
Rina TriasihDepartment of Pediatrics, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, Indonesia.
Eric WobudeyaMulago National Referral Hospital, Kampala, Uganda.
Marcia C Bellotti de OliveiraDepartment of Pediatrics, Souza Marques Medical School, Rio de Janeiro, Brazil.
Yana SheremetaAll-Ukrainian Network of People Living With HIV/AIDS, Kyiv, Ukraine.
Mercedes C BecerraDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, USA.
Silvia S ChiangDepartment of Pediatrics, Alpert Medical School of Brown University, Providence, Rhode Island, USA.ORCID 0000-0002-2318-3802
University of California, San Francisco · USBrown University · USFundação Técnico Educacional Souza Marques · BRHarvard University · USMulago Hospital · UGUniversitas Gadjah Mada · ID

Funding

TRAINEESHIPS IN AIDS PREVENTION STUDIEST32MH019105 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Carol Suzanne Camlin, Glenn-Milo Santos · 1989 to 2026
$15.3M
Host Proteomic Biosignatures for a Urine-based Diagnosis of Pulmonary Tuberculosis in ChildrenK23HL153581 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JAGANATH, DEVAN · 2020 to 2024
$946k
Teens on TB Treatment: Predicting Adherence through Clinical Decision AnalysisK01TW010829 · FIC · RHODE ISLAND HOSPITAL · PI CHIANG, SILVIA SHINPEI · 2017 to 2021
$775k
FIC NIH HHS K01 TW010829NIH HHS K23HL153581NIMH NIH HHS T32 MH019105
6 · The paper itself

Abstract

Global efforts to eliminate tuberculosis (TB) must address the unique barriers that children (ages 0 through 9 years) and adolescents/young adults (AYA; ages 10 through 24 years) face in adhering to treatment for TB infection and disease. We conducted a narrative review to summarize current knowledge on the social determinants of treatment adherence among these age groups to guide efforts and policy to address their unique needs. Our findings revealed that research on TB treatment adherence among children and AYA is still in its nascent stage. The current literature revealed structural/community-, health system-, household-, and individual-level factors that influence treatment adherence and varied with developmental stage. There is a need to develop multilevel interventions to address the unique challenges that children and AYA face in adhering to TB treatment.

Indexed as

Latent TuberculosisTuberculosisAdolescentChildFamily CharacteristicsHumansInfant, NewbornSocial Determinants of HealthYoung Adultadolescentschildrenmedication adherencesocial determinantstuberculosis

Identifiers

PMID36314549
PMCPMC9620428
OpenAlexW4307889612

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.