Evidence map›Paper›PMID 36314542›Full record

ArticleActa orthopaedica2022

Inducible displacement CT increases the diagnostic accuracy of aseptic loosening in primary total hip arthroplasty.

Olof Sandberg, Sofia Carlsson, Ellen Harbom, Vendela Cappelen, Simon Tholén, Henrik Olivecrona, Per Wretenberg

Registry-linked trialAbstract read
In one paragraph

Article in Acta orthopaedica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06924567 (The Accuracy of CT-based Implant Movement for the Evaluation of Cup and Stem Stability, When Plain Radiography is Not Conclusive for Loosening, in Patients Scheduled for Revision Hip Arthroplasty. A Multicenter Study), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06924567 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Accuracy of CT-based Implant Movement for the Evaluation of Cup and Stem Stability, When Plain Radiography is Not Conclusive for Loosening, in Patients Scheduled for Revision Hip Arthroplasty. A Multicenter Study

Typeobservational_patient_registrySponsorGeorgios Tsikandylakis, MD PhDRan2026 to 2029Enrolled600ConditionsLoosening, Prosthesis, Hip ArthropathyArmsImplant motion provocation CT
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Evaluation of conventional and CT-based radiostereometric analysis for inducible displacement measurements after total hip arthroplasty.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Olof SandbergSectra AB, Linköping. olof.sandberg@sectra.com.
Sofia CarlssonDepartment of Radiology, Örebro University Hospital.
Ellen HarbomSchool of Medical Sciences, Örebro University.
Vendela CappelenSchool of Medical Sciences, Örebro University.
Simon TholénDepartment of Radiology, Örebro University Hospital.
Henrik OlivecronaDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Sweden.
Per WretenbergDepartment of Medical Sciences, Section of Orthopaedics, Örebro University Hospital.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeInducible displacement CT compares 2 CTs acquired in series but with alternated rotation of the femur. This provides visual and quantitative clues as to the mechanical situation, i.e., loosening, of a total hip arthroplasty. We report the accuracy of this method as well as the experience of integrating it into a clinical workflow. PATIENTS AND

methodsThis was a retrospective single centre study of 72 cases of suspected aseptic loosening were the surgeon after reviewing a standard plain radiograph saw a need for more information. The displacement CT and plain radiograph were compared either to intraoperative findings or a 1-3 year follow up questionnaire for patients that did not have revision surgery. Patients reporting degradation in status since the time of the displacement CT were called for a follow up plain radiograph. Sensitivity and specificity were assessed, and user experience gathered.

resultsOf 72 enrolled patients 15 were lost to follow up. Of the remaining 57, 17 were judged by in-traoperative findings or follow-up to have had loose implants. For plain radiography the sensitivity and specificity were 59% (95% CI 35-82) and 85% (74-96). For displacement CT the corresponding values were 77% (56-97), and 100% (100-100) respectively. The tool was adaptable to clinical routine.

conclusionDisplacement CT with alternated rotations of the femur is a viable option to improve the diagnostic process for identifying aseptic loosening in a total hip arthroplasty.

Indexed as

Arthroplasty, Replacement, HipHip ProsthesisFollow-Up StudiesHumansProsthesis FailureReoperationRetrospective StudiesTomography, X-Ray Computed

Identifiers

PMID36314542
PMCPMC9620441

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.