Evidence map›Paper›PMID 36314047›Full record

ArticlePaediatric anaesthesia2023

Postanesthesia complications in pediatric patients with previous SARS-CoV-2 infection: A cohort study.

Giuliana Geng-Ramos, Jonathan Nelson, Angela C Lee, Nina Deutsch, Chaitanya Challa, Sophie Pestieau, Md Sohel Rana, Mark Hubbard, Jessica A Cronin

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Paediatric anaesthesia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Giuliana Geng-RamosDivision of Anesthesiology, Pain and Perioperative Medicine, Children's National Hospital, The George Washington University, Washington, District of Columbia, USA.ORCID 0000-0003-0692-8371
Jonathan NelsonDivision of Anesthesiology, Pain and Perioperative Medicine, Children's National Hospital, The George Washington University, Washington, District of Columbia, USA.
Angela C LeeDivision of Anesthesiology, Pain and Perioperative Medicine, Children's National Hospital, The George Washington University, Washington, District of Columbia, USA.
Nina DeutschDivision of Anesthesiology, Pain and Perioperative Medicine, Children's National Hospital, The George Washington University, Washington, District of Columbia, USA.ORCID 0000-0001-7137-4737
Chaitanya ChallaDivision of Anesthesiology, Pain and Perioperative Medicine, Children's National Hospital, The George Washington University, Washington, District of Columbia, USA.
Sophie PestieauDivision of Anesthesiology, Pain and Perioperative Medicine, Children's National Hospital, The George Washington University, Washington, District of Columbia, USA.
Md Sohel RanaJoseph E. Robert Jr, Center for Surgical Care, Children's National Hospital, Washington, District of Columbia, USA.
Mark HubbardDivision of Anesthesiology, Pain and Perioperative Medicine, Children's National Hospital, The George Washington University, Washington, District of Columbia, USA.
Jessica A CroninDivision of Anesthesiology, Pain and Perioperative Medicine, Children's National Hospital, The George Washington University, Washington, District of Columbia, USA.ORCID 0000-0002-2583-084X
George Washington University Hospital · USChildren's National · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChildren with SARS-CoV-2 infection are at increased risk for postanesthesia complications. There is minimal data regarding how long that elevated complication risk persists beyond initial SARS-CoV-2 diagnosis.

aimsWe investigated postanesthesia complications in children with SARS-CoV-2 infection within 90 days of diagnosis.

methodsWe completed a single-center, retrospective, case-control study of pediatric patients with confirmed SARS-CoV-2 infection within 90 days undergoing anesthesia between January 3-October 7, 2020. Each SARS-CoV-2 positive patient was matched 1:2 by age and type of procedure with a non-SARS-CoV-2 cohort. The primary outcome was the rate of all postanesthesia complications within 30 days of the procedure, defined as unplanned escalations of care within 48 h, cardiac, respiratory, thrombotic, and hemorrhagic events within 30 days. Secondary outcomes were 30-day mortality and hospital length of stay.

resultsOf the 341 patients included, 114 patients were SARS-CoV-2 positive and 227 were SARS-CoV-2 negative. Patients with a positive test 0-7 days prior to anesthesia had an increased risk difference in all postanesthesia complications within 30 days (19.9, 95% CI [4.7, 35.1], p = .001) and increased risk difference in length of hospital stay (7.8, 95% CI [1.2, 14.4], p < .001). Patients who underwent anesthesia greater than 42 days from SARS-CoV-2 diagnosis had an increased risk difference in cardiac complications within 30 days (4.3, 95% CI [0.9, 10.0], p = .029). There was no increased hospital length of stay among SARS-CoV-2 positive patients diagnosed greater than 8 days before anesthetic. There were no deaths within 30 days of anesthetic.

conclusionsPostanesthesia complications are higher in children who undergo anesthesia within 7 days of SARS-CoV-2 diagnosis. Additional cardiac risk may persist beyond the immediate period of initial diagnosis. Larger samples are needed to further evaluate the risk of delayed postanesthesia complications and guide optimal timing of surgery.

Indexed as

COVID-19Case-Control StudiesChildCohort StudiesCOVID-19 TestingHumansRetrospective StudiesSARS-CoV-2complicationsCOVID-19postanesthesiaSARS-CoV-2

Identifiers

PMID36314047
PMCPMC9877943
OpenAlexW4307775071

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.