Evidence map›Paper›PMID 36313975›Full record

ArticleJournal of orthopaedic translation2023

Construction of biomimetic cell-sheet-engineered periosteum with a double cell sheet to repair calvarial defects of rats.

Jun Zhang, Yanran Huang, Yuping Wang, Jingtao Xu, Tianji Huang, Xiaoji Luo

Abstract read
In one paragraph

Article in Journal of orthopaedic translation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
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  3. Article
  4. Review
  5. Article
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  8. Article
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  10. Article
  11. Stem Cells and Bone Tissue Engineering.Life (Basel, Switzerland) · 2024
    Review
  12. Article
  13. Review
  14. Article
  15. Biodegradable Cements for Bone Regeneration.Journal of functional biomaterials · 2023
    Review
  16. 2023 January issue Journal of Orthopaedic Translation.Journal of orthopaedic translation · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jun ZhangThe First Affiliated Hospital of Chongqing Medical University, Orthopedic Laboratory of Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Yanran HuangThe First Affiliated Hospital of Chongqing Medical University, Orthopedic Laboratory of Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Yuping WangThe First Affiliated Hospital of Chongqing Medical University, Orthopedic Laboratory of Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Jingtao XuThe First Affiliated Hospital of Chongqing Medical University, Orthopedic Laboratory of Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Tianji HuangThe First Affiliated Hospital of Chongqing Medical University, Orthopedic Laboratory of Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Xiaoji LuoThe First Affiliated Hospital of Chongqing Medical University, Orthopedic Laboratory of Chongqing Medical University, Chongqing, 400016, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The periosteum plays a crucial role in the development and injury healing process of bone. The purpose of this study was to construct a biomimetic periosteum with a double cell sheet for bone tissue regeneration. Methods: Results: Conclusion: The double cell sheet could promote to repair calvarial defects of rats and accelerate bone regeneration. The translational potential of this article: We successfully constructed a biomimetic cell-sheet-engineered periosteum with a double cell sheet by a simple, low-cost and effective method. This biomimetic periosteum may be a promising therapeutic strategy for the treatment of bone defects, which may be used in clinic in the future.

Indexed as

adiposetissue derivedstromalcells, ADSCsalkaline phosphatase, ALPBiomimetic periosteumbonemarrowmesenchymlstemcells, BMSCsbone mineral density, BMDBone regenerationbonevolume fraction, BV/TVcell sheet technology, CSTcytokeratin 19, CK-19Double cell sheetextracellular matrix, ECMhAMSCs sheethematoxylin and eosin, HEhuman amniotic mesenchymal stem cells, hAMSCshuman ethmoid sinus mucosa derived mesenchymal stem cells, hESMSCsOsteogenic cell sheetperiodontal ligament-derived cells, PDLCspolylactic-co-glycolic acid, PLGAscanning electron microscopy, SEMTrabecular number, Tb.NTrabecular thickness, Tb.ThVascular cell sheet

Identifiers

PMID36313975
PMCPMC9582589

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.