ArticleFrontiers in pediatrics2022
Applicability of the hour of life approach in hyperbilirubinemia among Filipino term infants.
Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Predictive value of the 24-hour bilirubin in the development of significant hyperbilirubinemia among Filipino term (≥37 weeks gestational age) infants: a prospective multi-center study.Pediatric research · 2026Article
- Evolution and contemporary landscape of neonatal hyperbilirubinemia management guidelines: a narrative review.Frontiers in pediatrics · 2026Review
- Smartphone-based screening of neonatal jaundice in three populations in low and middle-income countries: a cross-sectional study.BMJ paediatrics open · 2025Article
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3 authors.
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Abstract
Background: Hyperbilirubinemia remains a common morbidity among infants. Additional research on bilirubin kinetics and associated risk factors will contribute to providing a more targeted management approach for the Filipino infant. Objective: To develop a Filipino bilirubin nomogram by studying bilirubin patterns during the first 5 days of life. Methodology: This prospective study recruited 1,412 stable, full-term infants (≥37 weeks age of gestation) born at the Philippine General Hospital (PGH). Using the Dräger-Minolta JM-103 jaundice meter, transcutaneous bilirubin (TcB) levels were determined at the 3rd, 6th, 12th, 24th, 36th, 48th, 72nd, 96th, and 120th hour of life (HOL). A bilirubin nomogram was created using the averages of 3 TcB forehead and sternal measurements at each time epoch. Simultaneous measurement of TcB and total serum bilirubin (TsB) on a subset of 106 infants was done to determine correlation. Results: Correlation coefficients were high between TsB and forehead TcB (r Conclusion: TcB is a reliable, non-invasive bilirubin screening tool. Among healthy, full-term, Filipino infants, their nomogram features a sudden increase in bilirubin values during the first 48 h, followed by a plateau. To aid in identification of infants at risk for significant hyperbilirubinemia, healthcare providers can assess breastfeeding adequacy and perform bilirubin screening at the 24th-48th HOL. Registration No. (RGAO-2016-0686).
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