ArticleInternational journal of biomedical imaging2022
Comparison of Diffusion Tensor Imaging Metrics in Normal-Appearing White Matter to Cerebrovascular Lesions and Correlation with Cerebrovascular Disease Risk Factors and Severity.
Article in International journal of biomedical imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Effects of computerized cognitive training on functional brain networks in patients with vascular cognitive impairment and no dementia.CNS neuroscience & therapeutics · 2024Trial
- White matter microstructure differences in obstructive sleep apnea severity groups assessed by diffusion tensor metrics and biophysical modeling.Scientific reports · 2026Article
- Multimodal Magnetic Resonance Imaging Signatures of White Matter Hyperintensities: Mechanistic Insights Into Pathobiological Heterogeneity.Journal of stroke · 2026Review
- Plasma placental growth factor as a susceptibility biomarker for longitudinal cognitive change.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Association between vascular risk factors burden and neurodegenerative diseases: results from ONDRI.Journal of neurology · 2025Article
- Detecting cognitive impairment in cerebrovascular disease using gait, dual tasks, and machine learning.BMC medical informatics and decision making · 2025Article
- White matter tract correlations with spoken language in cerebrovascular disease.Brain communications · 2025Article
- Electroacupuncture treatment can improve cognitive impairment in spontaneously hypertensive rats: a preliminary DTI study.Frontiers in neuroscience · 2025Article
- Effect of the duration of hypertension on white matter structure and its link with cognition.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Article
- Mapping neurodegeneration with diffusion MRI: biomarkers, mechanisms, and clinical translation.Frontiers in neurologyReview
Corrections and comments
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Authors and funding
35 authors.
Funding
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Abstract
Alterations in tissue microstructure in normal-appearing white matter (NAWM), specifically measured by diffusion tensor imaging (DTI) fractional anisotropy (FA), have been associated with cognitive outcomes following stroke. The purpose of this study was to comprehensively compare conventional DTI measures of tissue microstructure in NAWM to diverse vascular brain lesions in people with cerebrovascular disease (CVD) and to examine associations between FA in NAWM and cerebrovascular risk factors. DTI metrics including fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), and radial diffusivity (RD) were measured in cerebral tissues and cerebrovascular anomalies from 152 people with CVD participating in the Ontario Neurodegenerative Disease Research Initiative (ONDRI). Ten cerebral tissue types were segmented including NAWM, and vascular lesions including stroke, periventricular and deep white matter hyperintensities, periventricular and deep lacunar infarcts, and perivascular spaces (PVS) using T
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Registered trials
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