Evidence map›Paper›PMID 36313610›Full record

ArticleJournal of acute medicine2022

Dual Antiplatelet Therapy in the Management of Acute Minor Ischemic Stroke and High-Risk Transient Ischemic Attack: An Expert Consensus Statement From Taiwan Stroke Society and Taiwan Society of Emergency Medicine.

Po-Lin Chen, Ying-Ju Chen, Chih-Ping Chung, Chen-June Seak, Jiann-Shing Jeng, Ming-Ju Hsieh, Li-Ming Lien, Jiann-Hwa Chen, Yu-Wei Chen, Te-Fa Chiu and 2 more

Abstract read
In one paragraph

Article in Journal of acute medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Po-Lin ChenNeurological Institute Division of Neurology Taichung Veterans General Hospital, Taichung Taiwan.
Ying-Ju ChenTaipei Veterans General Hospital Department of Emergency Medicine Taipei Taiwan.
Chih-Ping ChungNeurological Institute Department of Neurology Taipei Veterans General Hospital, Taipei Taiwan.
Chen-June SeakNew Taipei Municipal Tucheng Hospital Department of Emergency Medicine New Taipei City Taiwan.
Jiann-Shing JengNational Taiwan University Hospital Department of Neurology and Stroke Center Taipei Taiwan.
Ming-Ju HsiehNational Taiwan University Hospital Department of Emergency Medicine Taipei Taiwan.
Li-Ming LienShin Kong Wu Ho-Su Memorial Hospital Department of Neurology Taipei Taiwan.
Jiann-Hwa ChenCathay General Hospital Department of Emergency Medicine Taipei Taiwan.
Yu-Wei ChenLandseed International Hospital Department of Neurology Taoyuan Taiwan.
Te-Fa ChiuChina Medical University Hospital Department of Emergency Medicine Taichung Taiwan.
Jiunn-Tay LeeTri-Service General Hospital Department of Neurology National Defense Medical Center, Taipei Taiwan.
Chip-Jin NgChang Gung University College of Medicine Taoyuan Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this review is to achieve a consensus between Taiwan Stroke Society (TSS) and Taiwan Society of Emergency Medicine (TSEM) to manage acute non-cardioembolic minor ischemic stroke (MIS) and high-risk transient ischemic attack (TIA). The methodology is to review the recent findings from clinical trials of dual antiplatelet therapy (DAPT) from 2010 to 2021 and updates in clinical practice guidelines from 2018 to 2022 for non-cardioembolic MIS/TIA management at the acute stage. Four leading clinical studies, CHANCE, POINT, THALES, and CHANCE-2 along with other relevant studies introducing DAPT, are discussed in this review. The risk-benefit profile between stroke recurrence reduction and major bleeding increase is also elucidated. TSS and TSEM concluded that for patients presenting with non-cardioembolic MIS or high-risk TIA who did not receive intravenous alteplase, initiation of DAPT within 24 hours after stroke onset and continued up to 21 days, followed by antiplatelet monotherapy, is effective in reducing recurrent ischemic stroke for a period of up to 90 days.

Indexed as

acute minor ischemic strokeconsensus statementdual antiplatelet therapytransient ischemic attack

Identifiers

PMID36313610
PMCPMC9561483

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.