ArticleFrontiers in neurology2022
Effects of short-term spinal cord stimulation on patients with prolonged disorder of consciousness: A pilot study.
Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- Short-Term Spinal Cord Stimulation Improves Consciousness Level in Prolonged Disorders of Consciousness.Neurocritical care · 2026Article
- A single-cell transcriptomic dataset profiling traumatic brain injury and NeuroD1-based gene therapy in mice.Scientific data · 2026Article
- Long-term outcomes and age-dependent recovery trajectories following short-term spinal cord stimulation in patients with disorders of consciousness.Frontiers in neurology · 2026Article
- Graph-Theoretical Signature from Neural and Vascular Signals Reveals Spinal Cord Stimulation Frequency-Specific Brain Network in Disorders of Consciousness Patients.Cyborg and bionic systems (Washington, D.C.) · 2026Article
- Non-invasive neuroregulation techniques applied to patients with consciousness disorders: a narrative review.Frontiers in human neuroscience · 2026Review
- Spinal cord stimulation for concurrent improvement of consciousness and spasticity following severe traumatic brain injury: a case study.Frontiers in neuroscience · 2026Article
- Clinical Outcome After Epidural Spinal Cord Stimulation in Patients With Severe Traumatic Brain Injury.Cureus · 2024Article
- Traumatic Brain Injury and Neuromodulation Techniques in Rehabilitation: A Scoping Review.Biomedicines · 2024Article
- Clinical effect of short-term spinal cord stimulation in the treatment of patients with primary brainstem hemorrhage-induced disorders of consciousness.Frontiers in neurology · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Spinal cord stimulation (SCS) can improve the level of awareness of prolonged disorder of consciousness (pDOC), but its application is restricted due to damage of invasive operation. Short-term spinal cord stimulation (st-SCS) in a minimally invasive manner will better balance the benefits and risks. Objectives: This study focuses on the safety and efficacy of st-SCS for pDOC and reveals the modulation characteristics of different frequencies of SCS. Methods: 31 patients received 2-week st-SCS treatment and 3-months follow-up. All patients were divided into two types of frequency treatment groups of 5 Hz and 70 Hz according to the postoperative electroencephalography (EEG) test. The efficacy was assessed based on the revised coma recovery scale (CRS-R). Results: The results showed a significant increase in CRS-R scores after treatment (Z = -3.668, Conclusion: st-SCS was safe and effective in improving patients with pDOC levels of consciousness, and was most effective for MCS-. Both 5 Hz and 70 Hz st-SCS can promote consciousness recovery, with 70 Hz showing a delayed effect in particular.
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