Evidence map›Paper›PMID 36313503›Full record

ArticleFrontiers in neurology2022

Surgical quadriceps lengthening can reduce quadriceps spasticity in chronic stroke patients. A case-control study.

Andrea Merlo, Martina Galletti, Paolo Zerbinati, Paolo Prati, Francesca Mascioli, Giacomo Basini, Chiara Rambelli, Stefano Masiero, Davide Mazzoli

Abstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrea MerloGait and Motion Analysis Laboratory, Sol et Salus Hospital, Rimini, Italy.
Martina GallettiGait and Motion Analysis Laboratory, Sol et Salus Hospital, Rimini, Italy.
Paolo ZerbinatiNeuro-Orthopedic Unit, Sol et Salus Hospital, Rimini, Italy.
Paolo PratiGait and Motion Analysis Laboratory, Sol et Salus Hospital, Rimini, Italy.
Francesca MascioliGait and Motion Analysis Laboratory, Sol et Salus Hospital, Rimini, Italy.
Giacomo BasiniGait and Motion Analysis Laboratory, Sol et Salus Hospital, Rimini, Italy.
Chiara RambelliGait and Motion Analysis Laboratory, Sol et Salus Hospital, Rimini, Italy.
Stefano MasieroSection of Rehabilitation, Department of Neuroscience, University of Padova, Padua, Italy.
Davide MazzoliGait and Motion Analysis Laboratory, Sol et Salus Hospital, Rimini, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Muscle overactivity is one of the positive signs of upper motor neuron lesions. In these patients, the loss of muscle length and extensibility resulting from soft tissue rearrangement has been suggested as a contributing cause of muscle overactivity in response to stretching. Objective: To assess the effects of surgical lengthening of the quadriceps femoris (QF) muscle-tendon unit by aponeurectomy on muscle spasticity. Methods: This is a case-control study on chronic stroke patients with hemiparesis that have undergone lower limb functional surgery over a 8-year period. CASEs underwent corrective surgery for both the foot and knee deviations, inclusive of a QF aponeurectomy. Controls (CTRLs) underwent corrective surgery for foot deviations only. QF spasticity was assessed with the Modified Tardieu Scale (MTS) before and 1 month after surgery. The Wilcoxon test was used to assess MTS variations over time and the Mann-Whitney test was used to verify the presence of group differences at the 1 month mark. Results: Ninety-three patients were included: 57 cases (30F, 1-34 years from lesion) and 36 controls (12F, 1-35 years from lesion). Before surgery, both CASEs and CTRLs had similar MTS scores (median MTS = 3) and functional characteristics. One month after surgery, QF spasticity was significantly lower in the CASEs compared to CTRLs ( Conclusions: Functional surgery inclusive of QF aponeurectomy can be effective in reducing or suppressing spasticity in chronic stroke patients. This is possibly a result of the reduction in neuromuscular spindle activation due to a decrease in muscle shortening, passive tension, and stiffness.

Indexed as

aponeurectomyModified Tardieu Scalespasticitystrokesurgery

Identifiers

PMID36313503
PMCPMC9606420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.