Evidence map›Paper›PMID 36313310›Full record

ArticleFrontiers in pharmacology2022

Monomethyl lithospermate alleviates ischemic stroke injury in middle cerebral artery occlusion mice

Fang Yang, Ze-Ran Chen, Xu-Hong Yang, Yue Xu, Ning-Jing Ran, Mei-Jun Liu, Shuo-Guo Jin, Hua-Nan Jia, Yang Zhang

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Cerebral [Translational stroke research · 2025
    Article
  7. Article
  8. InOpen veterinary journal · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fang YangHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Ze-Ran ChenSchool of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Xu-Hong YangHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yue XuHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Ning-Jing RanHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Mei-Jun LiuHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Shuo-Guo JinHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Hua-Nan JiaHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yang ZhangHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stroke is a fatal neurological disease, which seriously threatens human health and life. Ischemic stroke (IS) is the most common type of stroke in clinic. Its pathogenesis is very complex, mainly caused by nerve damage caused by brain blood supply disorder. Previous studies have confirmed that natural products play important roles in improving neurological disorders. Furthermore, our previous results also suggested that

Indexed as

ischemia-reperfusionischemic strokeneural damageOGR/RPI3K/Akt pathwaystroke

Identifiers

PMID36313310
PMCPMC9606694

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.