Evidence map›Paper›PMID 36313203›Full record

ArticleAmerican journal of clinical and experimental urology2022

Analysis of the influence of marital status on prognosis of prostate cancer patients based on big data.

Yang Li, Xueping Ma, Chao Guan, Xuezhen Yang

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Article in American journal of clinical and experimental urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Yang LiDepartment of Urology, The Second Affiliated Hospital of Bengbu Medical College Bengbu 233020, Anhui, China.
Xueping MaDepartment of Urology, The Second Affiliated Hospital of Bengbu Medical College Bengbu 233020, Anhui, China.
Chao GuanDepartment of Urology, The Second Affiliated Hospital of Bengbu Medical College Bengbu 233020, Anhui, China.
Xuezhen YangDepartment of Urology, The Second Affiliated Hospital of Bengbu Medical College Bengbu 233020, Anhui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the effect of different marital status on the prognosis of patients with prostate cancer.

methodsThe general data of 169,533 patients with prostate cancer confirmed by biopsy or surgery in SEER database were retrospectively analyzed. The COX univariate analysis was performed first, and the meaningful variables of the univariate analysis were incorporated into the Cox proportional hazards model for multivariate analysis, and the independent factors affecting the prognosis of patients with prostate cancer were obtained.

resultsThe collected patients accounted for 59% of married patients and 22% of unmarried patients. COX multivariate analysis, the results showed: age (HR: 1.063; P<0.001), tumor differentiation grade (HR: 1.367; P<0.001), marital status: married (HR: 0.648; P<0.001), unmarried (HR: 0.602; P<0.001), bone metastasis (HR: 6.077; P<0.001), brain metastasis (HR: 2.296; P<0.001), liver metastasis (HR: 2.582; P<0.001), lung metastasis (HR: 1.256; P<0.001), distant lymph node metastasis (HR: 1.698; P<0.001), T stage (HR: 1.047; P>0.005), N stage (HR: 0.970; P>0.005), M stage (HR: 0.880; P>0.005) were all factors affecting the prognosis of patients with prostate cancer. The average survival time of married patients was 16.05±10.32 months, and the average survival time of unmarried patients was 15.46±10.37 months. The average survival time of married patients was longer than that of unmarried patients (X

conclusionBased on big data analysis, marital status has a great influence on postoperative prostate cancer patients, and the survival time of married prostate cancer patients is longer than that of unmarried patients.

Indexed as

marital statusProstate cancerSEER databasesurvival analysis

Identifiers

PMID36313203
PMCPMC9605935

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