Evidence map›Paper›PMID 36313165›Full record

ArticleACS central science2022

Detecting the First Hydration Shell Structure around Biomolecules at Interfaces.

Daniel Konstantinovsky, Ethan A Perets, Ty Santiago, Luis Velarde, Sharon Hammes-Schiffer, Elsa C Y Yan

Open access · diamondAbstract read
In one paragraph

Article in ACS central science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. First Hydration Shell Integrity: Key to Protein Stability.Journal of the American Chemical Society · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Stepwise Hydration Reveals Conformational Switching in Chiral Prolinol.Journal of the American Chemical Society · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Concluding remarks forFaraday discussions · 2024
    Article
  19. Fully First-Principles Surface Spectroscopy with Machine Learning.The journal of physical chemistry letters · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Daniel KonstantinovskyDepartment of Chemistry, Yale University, New Haven, Connecticut 06520, United States.ORCID https://orcid.org/0000-0001-5718-7791
Ethan A PeretsDepartment of Chemistry, Yale University, New Haven, Connecticut 06520, United States.ORCID https://orcid.org/0000-0001-9554-776X
Ty SantiagoDepartment of Chemistry, University at Buffalo, Buffalo, New York 14260, United States.
Luis VelardeDepartment of Chemistry, University at Buffalo, Buffalo, New York 14260, United States.ORCID https://orcid.org/0000-0001-6329-3486
Sharon Hammes-SchifferDepartment of Chemistry, Yale University, New Haven, Connecticut 06520, United States.ORCID https://orcid.org/0000-0002-3782-6995
Elsa C Y YanDepartment of Chemistry, Yale University, New Haven, Connecticut 06520, United States.ORCID https://orcid.org/0000-0002-3583-1627
Yale University · USUniversity at Buffalo, State University of New York · US

Funding

PREDOCTORAL PROGRAM IN BIOPHYSICST32GM008283 · NIGMS · YALE UNIVERSITY · PI XIONG, YONG · 1988 to 2022
$10.5M
Coupled Protons and Electrons in Biological SystemsR35GM139449 · NIGMS · YALE UNIVERSITY · PI HAMMES-SCHIFFER, SHARON · 2021 to 2025
$2.1M
NIGMS NIH HHS R35 GM139449NIGMS NIH HHS T32 GM008283
6 · The paper itself

Abstract

Understanding the role of water in biological processes remains a central challenge in the life sciences. Water structures in hydration shells of biomolecules are difficult to study

Identifiers

PMID36313165
PMCPMC9615115
OpenAlexW4294733073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.