Evidence map›Paper›PMID 36313129›Full record

ArticleJournal of kidney cancer and VHL2022

Partial Nephrectomy for T1b/T2 Renal Mass: An Added Shift from Radical Nephrectomy.

Mohamed Sharafeldeen, Wael Sameh, Vahid Mehrnoush, Amer Alaref, Radu Rozenberg, Asmaa Ismail, Hazem Elmansy, Walid Shahrour, Ahmed Zakaria, Osama Elmeslemany and 4 more

Abstract read
In one paragraph

Article in Journal of kidney cancer and VHL, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mohamed SharafeldeenDepartment of Urology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Wael SamehDepartment of Urology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Vahid MehrnoushDepartment of Urology, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
Amer AlarefDepartment of Urology, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
Radu RozenbergDepartment of Urology, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
Asmaa IsmailDepartment of Urology, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
Hazem ElmansyDepartment of Urology, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
Walid ShahrourDepartment of Urology, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
Ahmed ZakariaDepartment of Urology, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
Osama ElmeslemanyDepartment of Urology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Nishigandha BuruteDepartment of Urology, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
Anatoly ShusterDepartment of Urology, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
Owen ProwseDepartment of Urology, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
Ahmed KotbDepartment of Urology, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of our study was to show our short-term experience in managing large renal masses (cT1b/T2) through partial nephrectomy (PN) over the last 3 years. Retrospective data collection for all patients managed by PN for renal masses larger than 4 cm over the last 3 years. Epidemiological data were collected. Surgical data including surgical and ischemic times as well as intra and postoperative complications were collected. Pre- and postoperative estimated glomerular filtration rate (eGFR) data were collected and correlated as well as postoperative complications and recurrence. We could identify 47 patients managed by PN for radiologically confirmed >4 cm renal masses. The mean age of the patients was 55.7 ± 13.4, including 29 males and 18 females. Masses were T1b and T2 in 40 and 7 patients, respectively. The mean tumor size was 6.2 ± 1.5 cm. Using renal nephrometry score; 8, 28, and 11 had low, moderate, and high complexity, respectively. Renal cell carcinoma (RCC) was identified in 42 patients. Five patients out of 42 cancerous cases (12%) had pathological T3 RCC. The mean preoperative and postoperative eGFR were 89.09 ± 12.41 and 88.50 ± 10.50, respectively (P 0.2). The median follow-up was 14 months and within that short time, no patient had evidence for cancer recurrence. PN for large renal masses is safe in experienced hands and should be attempted in a higher percentage of patients, regardless of the tumor complexity. No cancer recurrence or deterioration of renal function was observed within our short-term follow-up.

Indexed as

eGFRlarge renal massnephrometry scorepartial nephrectomyradical nephrectomy

Identifiers

PMID36313129
PMCPMC9550639

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.