ArticleFrontiers in aging neuroscience2022
Monocytohigh-density lipoprotein ratio has a high predictive value for the diagnosis of multiple system atrophy and the differentiation from Parkinson's disease.
Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neutrophil to lymphocyte ratio in parkinson's disease: a systematic review and meta-analysis.BMC neurology · 2023Pooled it
- Monocyte-to-high-density lipoprotein cholesterol ratio predicts hematoma expansion and poor outcomes in patients with spontaneous intracerebral hemorrhage.BMC neurology · 2026Article
- Role of CXCR3 and CXCR6 on Circulating T Cells in Patients With Parkinson's Disease.Scandinavian journal of immunology · 2026Article
- The neutrophil-to-lymphocyte ratio in Parkinson's disease: a systematic review and meta-analysis of its association with differential diagnosis, severity, and prognosis.Clinical parkinsonism & related disorders · 2026Review
- GATD3A-mediated monocyte homeostasis and compartmentalized erythrocyte alpha-synuclein discriminate early Parkinson's disease from MSA-P.Frontiers in immunology · 2026Article
- Impact of Dementia on Perioperative Complications in Elderly Patients Undergoing Total Knee Arthroplasty: A Retrospective National Inpatient Sample Database Study.Geriatric orthopaedic surgery & rehabilitation · 2026Article
- Peripheral inflammatory markers and clinical phenotypes reflecting the impact of diabetes on Parkinson's disease.Journal of Parkinson's disease · 2025Article
- Potential Role of Transferrin and Vascular Cell Adhesion Molecule 1 in Differential Diagnosis Among Patients with Tauopathic Atypical Parkinsonian Syndromes.Diagnostics (Basel, Switzerland) · 2025Article
- Distinct spatial transcriptomic patterns of substantia Nigra in Parkinson disease and Parkinsonian subtype of multiple system atrophy.Acta neuropathologica communications · 2025Article
- The Relationship Between Systemic Inflammatory Index and Other Inflammatory Markers with Clinical Severity of the Disease in Patients with Parkinson's Disease.Biomedicines · 2025Article
- The Significance of High-Density Lipoprotein-Derived Inflammatory Parameters in Atypical Parkinsonisms-Pilot Study.Journal of clinical medicine · 2025Article
- Red cell distribution width/platelet ratio predicts decompensation of metabolic dysfunction-associated steatotic liver disease-related compensated advanced chronic liver disease.World journal of gastroenterology · 2025Article
- Peripheral blood cell profile and monocyte-high-density lipoprotein ratio in Alzheimer's disease: a hospital-based case-control study.Archives of medical science : AMS · 2025Article
- Inflammatory lipid biomarkers and transplant-free mortality risk in hepatitis B-related cirrhosis and hepatic encephalopathy.Frontiers in medicine · 2025Article
- Platelet Dynamics in Neurodegenerative Disorders: Investigating the Role of Platelets in Neurological Pathology.Journal of clinical medicine · 2024Review
- The interplay between monocytes, α-synuclein and LRRK2 in Parkinson's disease.Biochemical Society transactions · 2023Review
- The Peripheral Immune Traits Changed in Patients with Multiple System Atrophy.Brain sciences · 2023Article
- Inflammation in multiple system atrophy.Frontiers in immunology · 2023Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and purpose: Inflammation is closely related to the pathogenesis of multiple system atrophy (MSA). As markers of inflammation, the monocyte to high-density lipoprotein ratio (MHR), neutrophil to lymphocyte ratio (NLR), and red cell distribution width to platelet ratio (RPR) have been proven to be associated with a large variety of diseases. The aim of this study was to explore the association between inflammatory markers (MHR, NLR, and RPR) and MSA, and the difference between MSA and Parkinson's disease (PD) was further compared by these inflammatory markers. Materials and methods: This study was divided into three groups: 47 patients with MSA, 125 patients with PD, and 124 healthy controls. The corresponding laboratory indicators of subjects were collected and analyzed to obtain MHR, NLR, and RPR values. Results: Compared with healthy controls, the MHR, NLR, and RPR were higher in the MSA group ( Conclusion: There may be peripheral inflammation in patients with MSA. Compared with NLR and RPR, MHR has higher predictive value for the diagnosis and differential diagnosis of MSA.
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