Evidence map›Paper›PMID 36312962›Full record

ArticleFrontiers in microbiology2022

Mirubactin C rescues the lethal effect of cell wall biosynthesis mutations in

Bernhard Kepplinger, Xin Wen, Andrew Robert Tyler, Byung-Yong Kim, James Brown, Peter Banks, Yousef Dashti, Eilidh Sohini Mackenzie, Corinne Wills, Yoshikazu Kawai and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
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  4. Staying in the loop to make ends meet: roles and regulation of GlmR inbioRxiv : the preprint server for biology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Bernhard KepplingerCentre for Bacterial Cell Biology, Newcastle University, Newcastle upon Tyne, United Kingdom.
Xin WenChemistry, School of Natural and Environmental Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
Andrew Robert TylerChemistry, School of Natural and Environmental Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
Byung-Yong KimOdyssey Therapeutics Inc., Newcastle upon Tyne, United Kingdom.
James BrownCentre for Bacterial Cell Biology, Newcastle University, Newcastle upon Tyne, United Kingdom.
Peter BanksFaculty of Medical Sciences, Bioscience Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Yousef DashtiCentre for Bacterial Cell Biology, Newcastle University, Newcastle upon Tyne, United Kingdom.
Eilidh Sohini MackenzieFaculty of Medical Sciences, Bioscience Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Corinne WillsChemistry, School of Natural and Environmental Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
Yoshikazu KawaiCentre for Bacterial Cell Biology, Newcastle University, Newcastle upon Tyne, United Kingdom.
Kevin John WaldronFaculty of Medical Sciences, Bioscience Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Nicholas Edward Ellis AllenbyOdyssey Therapeutics Inc., Newcastle upon Tyne, United Kingdom.
Ling Juan WuCentre for Bacterial Cell Biology, Newcastle University, Newcastle upon Tyne, United Kingdom.
Michael John HallChemistry, School of Natural and Environmental Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
Jeff ErringtonCentre for Bacterial Cell Biology, Newcastle University, Newcastle upon Tyne, United Kingdom.
Newcastle University · GB

Funding

Wellcome Trust 209500/Z/17/Z
6 · The paper itself

Abstract

Growth of most rod-shaped bacteria is accompanied by the insertion of new peptidoglycan into the cylindrical cell wall. This insertion, which helps maintain and determine the shape of the cell, is guided by a protein machine called the rod complex or elongasome. Although most of the proteins in this complex are essential under normal growth conditions, cell viability can be rescued, for reasons that are not understood, by the presence of a high (mM) Mg

Indexed as

B. subtiliscell wall mutantschemical biological activitymirubactinsiderophore

Identifiers

PMID36312962
PMCPMC9609785
OpenAlexW4304956807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.