Evidence map›Paper›PMID 36312895›Full record

ArticleOxidative medicine and cellular longevity2022

Physical Training Reduces Chronic Airway Inflammation and Mediators of Remodeling in Asthma.

Renilson Moraes-Ferreira, Maysa Alves Rodrigues Brandao-Rangel, Thiago Gonçalves Gibson-Alves, Anamei Silva-Reis, Victor Hugo Souza-Palmeira, Helida Cristina Aquino-Santos, Claudio Ricardo Frison, Luis Vicente Franco Oliveira, Regiane Albertini, Rodolfo P Vieira

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07064057 (Effects of Aerobic Training With and Without Sniff Maneuver on Dyspnea, Functional Capacity and Quality of Life Among Asthma Patients), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07064057 nacompletednot on this mapstarted 2023, after this paper: background citation

Effects of Aerobic Training With and Without Sniff Maneuver on Dyspnea, Functional Capacity and Quality of Life Among Asthma Patients

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2023Enrolled28ConditionsAsthmaArmsAerobic exercise combined with the sniff maneuver technique, Aerobic exercise
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Synergistic Effects of High-Intensity Interval Training andInternational journal of molecular sciences · 2025
    Trial
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  4. Review
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  8. Review
  9. Article
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  11. Article
  12. Review
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  15. Review
  16. Exercise Rehabilitation and Chronic Respiratory Diseases: Effects, Mechanisms, and Therapeutic Benefits.International journal of chronic obstructive pulmonary disease · 2023
    Review
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Renilson Moraes-FerreiraFederal University of São Paulo (UNIFESP), Post-graduation Program in Sciences of Human Movement and Rehabilitation, Santos, SP, Brazil.ORCID https://orcid.org/0000-0001-8017-012X
Maysa Alves Rodrigues Brandao-RangelFederal University of São Paulo (UNIFESP), Post-graduation Program in Sciences of Human Movement and Rehabilitation, Santos, SP, Brazil.ORCID https://orcid.org/0000-0002-9284-8695
Thiago Gonçalves Gibson-AlvesFederal University of São Paulo (UNIFESP), Post-graduation Program in Sciences of Human Movement and Rehabilitation, Santos, SP, Brazil.
Anamei Silva-ReisFederal University of São Paulo (UNIFESP), Post-graduation Program in Sciences of Human Movement and Rehabilitation, Santos, SP, Brazil.
Victor Hugo Souza-PalmeiraFederal University of São Paulo (UNIFESP), Post-graduation Program in Sciences of Human Movement and Rehabilitation, Santos, SP, Brazil.ORCID https://orcid.org/0000-0001-9805-6317
Helida Cristina Aquino-SantosFederal University of São Paulo (UNIFESP), Post-graduation Program in Sciences of Human Movement and Rehabilitation, Santos, SP, Brazil.ORCID https://orcid.org/0000-0002-9191-3336
Claudio Ricardo FrisonFederal University of São Paulo (UNIFESP), Post-graduation Program in Sciences of Human Movement and Rehabilitation, Santos, SP, Brazil.ORCID https://orcid.org/0000-0002-1246-2697
Luis Vicente Franco OliveiraUnievangelica, Post-graduate Program in Human Movement and Rehabilitation and in Pharmaceutical Sciences, Anápolis, GO, Brazil.ORCID https://orcid.org/0000-0002-3852-9415
Regiane AlbertiniFederal University of São Paulo (UNIFESP), Post-graduation Program in Sciences of Human Movement and Rehabilitation, Santos, SP, Brazil.ORCID https://orcid.org/0000-0002-4143-0387
Rodolfo P VieiraFederal University of São Paulo (UNIFESP), Post-graduation Program in Sciences of Human Movement and Rehabilitation, Santos, SP, Brazil.ORCID https://orcid.org/0000-0001-6379-1143
Universidade Federal de São Paulo · BRUniversidade Evangelica de Goiás · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several benefits of aerobic training for asthmatic patients have been demonstrated. However, its effects on systemic inflammation and on airway remodeling mediators and lung mechanics are unknown. This prospective study included 21 intermittent and mild asthma patients, and as primary outcomes, the evaluation of pro- and anti-inflammatory and pro- and antifibrotic mediators in exhaled breath condensate (EBC) and blood were performed, beyond the cell counting in blood and in induced sputum. Aerobic training was performed for 3 months, 3 times per week. Aerobic training increased the levels of anti-inflammatory cytokines and of antifibrotic mediators in the breath condensate: IL-1ra (

Indexed as

AsthmaRelaxinBreath TestsCytokinesExhalationHumansInflammationInterleukin-10Interleukin-13Interleukin 1 Receptor Antagonist ProteinInterleukin-4Interleukin-5Interleukin-6LungNitric OxideProspective StudiesCytokinesInterleukin-10Interleukin-13Interleukin 1 Receptor Antagonist ProteinInterleukin-4Interleukin-5Interleukin-6Nitric OxideRelaxinTumor Necrosis Factor-alphaVascular Endothelial Growth Factor A

Identifiers

PMID36312895
PMCPMC9613382
OpenAlexW4306906556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.