ArticleTherapeutic advances in medical oncology2022
Reconsidering T component of cancer staging for T3/T4 non-small-cell lung cancer with additional nodule.
Article in Therapeutic advances in medical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Prognostic factors and survival prediction of resected non-small cell lung cancer with ipsilateral pulmonary metastases: a study based on the Surveillance, Epidemiology, and End Results (SEER) database.BMC pulmonary medicine · 2023Trial
- Subgroup and Prognostic Factor Analysis in T4 Lung Cancer Based on the 9th Tumour-Node-Metastasis Classification.Interdisciplinary cardiovascular and thoracic surgery · 2025Article
- Survival analysis between single-factor and multi-factor groups in Stage T3N0M0 non-small cell lung cancer.Turk gogus kalp damar cerrahisi dergisi · 2025Article
- Discriminating Central Lung Cancer Tumors from Atelectasis using Radiomics Analysis on Contrast-free CTCurrent medical imaging · 2025Article
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17 authors.
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Abstract
Background: Non-small-cell lung cancer (NSCLC) with additional nodule(s) located in the same lobe or ipsilateral different lobe were designated as T3 and T4, respectively, which was merely defined by anatomical location of additional nodule(s), regardless of other prognostic factors. Methods: A total of 4711 patients with T1-4, N0-2, M0 NSCLC undergoing complete resection were identified between 2009 and 2014, including 145 patients with additional nodule(s) in the same lobe (T3-Add) and 174 patients with additional tumor nodule(s) in ipsilateral different lobe (T4-Add). Overall survival (OS) was compared using multivariable Cox regression models and propensity score matching analysis (PSM). Results: T3-Add patients [T3-Add Conclusion: NSCLC patients with additional nodule(s) in the same lobe and ipsilateral different lobe (maximum tumor diameter ⩽ 3 cm) should be further validated and considered restaging as T2b and T3 in the forthcoming 9th tumor, node, and metastasis staging system.
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