ArticleACS omega2022
Perylene-Derived Hydrophilic Carbon Dots with Polychromatic Emissions as Superior Bioimaging and NIR-Responsive Photothermal Bactericidal Agent.
Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Carbon Dots: Emerging Nanomaterials for Ovarian Cancer Diagnosis and Therapy.Current drug targets · 2026Review
- High Quantum Yield Nitrogen and Boron Codoped Orange Fluorescent Carbon Quantum Dots for Antibacterial and Bacterial Imaging.ACS omega · 2025Article
- Nanomaterials in PCR: exploring light-to-heat conversion mechanisms and microfluidic integration.Microsystems & nanoengineering · 2025Review
- Functionalization and solubilization of polycyclic aromatic compounds by sulfoniumization.Chemical science · 2025Article
- Article
- Carbon quantum dots in bioimaging and biomedicines.Frontiers in bioengineering and biotechnology · 2023Review
- Near-Infrared Dyes: Towards Broad-Spectrum Antivirals.International journal of molecular sciences · 2022Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Little progress has been achieved on the synthesis of hydrophilic carbon dots (CDs), derived from polycyclic aromatic hydrocarbons, as an excellent photothermal agent. In this study, a strategy was developed to synthesize highly photoluminescent greenish-yellow emissive CDs based on nitration followed by hydrothermal carbonization of the polycyclic aromatic hydrocarbon precursor, perylene. The perylene-derived CDs (PY-CDs) exhibited an excellent NIR-light (808 nm) harvesting property toward high photothermal conversion efficiency (PCE = ∼56.7%) and thus demonstrated remarkable NIR-light responsive photothermal bactericidal performance. Furthermore, these fluorescent PY-CD nanoprobes displayed excitation-dependent polychromatic emissions in the range of 538-600 nm, with the maximum emission at 538 nm. This enables intense multicolor biological imaging of cellular substances with long-term photostability, nontoxicity, and effective subcellular distribution. The bactericidal action of PY-CDs is likely due to the elevated reactive oxygen species amplification in cooperation with the hyperthermia effect. This study offers a potential substitute for multicolor imaging-guided metal-free carbon-based photothermal therapy.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.