Evidence map›Paper›PMID 36312295›Full record

ReviewFrontiers in cardiovascular medicine2022

Right ventricular function in transcatheter mitral and tricuspid valve edge-to-edge repair.

Lukas Stolz, Philipp M Doldi, Ludwig T Weckbach, Thomas J Stocker, Daniel Braun, Martin Orban, Mirjam G Wild, Christian Hagl, Steffen Massberg, Michael Näbauer and 2 more

Abstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Impact of age on outcomes after transcatheter tricuspid valve edge-to-edge repair: insights from EuroTR.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Article
  2. Review
  3. Right ventricular to pulmonary artery coupling in patients with different types of aortic stenosis undergoing TAVI.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Article
  4. Article
  5. Identifying Responders to Transcatheter Interventions for Secondary Mitral Regurgitation.Current treatment options in cardiovascular medicine · 2025
    Review
  6. RV-PA uncoupling is associated with increased mortality in transthyretin amyloid cardiomyopathy treated with tafamidis.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lukas StolzMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Philipp M DoldiMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Ludwig T WeckbachMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Thomas J StockerMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Daniel BraunMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Martin OrbanMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Mirjam G WildMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Christian HaglGerman Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.
Steffen MassbergMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Michael NäbauerMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Jörg HausleiterMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Mathias OrbanGerman Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since transcatheter edge-to-edge repair (TEER) has become a valuable therapy in the treatment of both, mitral (MR) and tricuspid regurgitation (TR), the question of optimized patient selection has gained growing importance. After years of attributing rather little attention to the right ventricle (RV) and its function in the setting of valvular heart failure, this neglect has recently changed. The present review sought to summarize anatomy and function of the RV in a clinical context and aimed at presenting the current knowledge on how the RV influences outcomes after TEER for atrioventricular regurgitation. The anatomy of the RV is determined by its unique shape, which necessitates to use three-dimensional imaging methods for detailed and comprehensive characterization. Complex parameters such as RV to pulmonary artery coupling (RVPAc) have been developed to combine information of RV function and afterload which is primary determined by the pulmonary vasculature and LV filling pressure. Beyond that, TR, which is closely related to RV function also plays an important role in the setting of TEER. While mitral valve transcatheter edge-to-edge repair (M-TEER) leads to reduction of concomitant TR in some patients, the prognostic value of TR in the setting of M-TEER remains unclear. Overall, this review summarizes the current state of knowledge of the outstanding role of RV function and associated TR in the setting of TEER and outlines the unsolved questions associated with right-sided heart failure.

Indexed as

edge-to-edge repairMitraClipmitral regurgitationPASCALright ventricular functiontricuspid regurgitation

Identifiers

PMID36312295
PMCPMC9596758

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.