Evidence map›Paper›PMID 36312292›Full record

ArticleFrontiers in cardiovascular medicine2022

Hemodynamics of transcatheter tricuspid valve replacement with Lux-Valve.

Wang Wei, Li Ning, Ning Xiaoping, Xu Zhiyun, Li Bailing, Cai Chengliang, Yang Fan, Zhou Guangwei, Bai Yifan, Han Lin and 2 more

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Transcatheter tricuspid valve replacement: will it prevail?Frontiers in cardiovascular medicine · 2025
    Review
  8. Tricuspid Valve Regurgitation: Current Understanding and Novel Treatment Options.Journal of the Society for Cardiovascular Angiography & Interventions
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wang WeiDepartment of Cardiovascular Surgery, Changhai Hospital, Naval Military Medical University, Shanghai, China.
Li NingDepartment of Cardiovascular Surgery, Changhai Hospital, Naval Military Medical University, Shanghai, China.
Ning XiaopingDepartment of Cardiovascular Surgery, Changhai Hospital, Naval Military Medical University, Shanghai, China.
Xu ZhiyunDepartment of Cardiovascular Surgery, Changhai Hospital, Naval Military Medical University, Shanghai, China.
Li BailingDepartment of Cardiovascular Surgery, Changhai Hospital, Naval Military Medical University, Shanghai, China.
Cai ChengliangDepartment of Cardiovascular Surgery, Changhai Hospital, Naval Military Medical University, Shanghai, China.
Yang FanDepartment of Cardiovascular Surgery, Changhai Hospital, Naval Military Medical University, Shanghai, China.
Zhou GuangweiDepartment of Cardiovascular Surgery, Changhai Hospital, Naval Military Medical University, Shanghai, China.
Bai YifanDepartment of Cardiovascular Surgery, Changhai Hospital, Naval Military Medical University, Shanghai, China.
Han LinDepartment of Cardiovascular Surgery, Changhai Hospital, Naval Military Medical University, Shanghai, China.
Qiao FanDepartment of Cardiovascular Surgery, Changhai Hospital, Naval Military Medical University, Shanghai, China.
Lu FanglinDepartment of Cardiovascular Surgery, Changhai Hospital, Naval Military Medical University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Transcatheter tricuspid valve intervention (TTVI) has emerged as an alternative treatment option for high-risk and inoperable patients with symptomatic tricuspid regurgitation (TR). However, scarce data in hemodynamic profiles were available on TTVI. In this paper, we attempt to report the hemodynamic profiles of LuX-Valve. Methods: 30 patients from July 2020 to July 2021 were enrolled in this study. The patient was diagnosed with severe symptomatic TR. The clinical, invasive hemodynamic, and echocardiographic data were collected. Results: The surgical success rate was 100%. The cardiac index and stroke volume increased sharply from 2.42(2.27, 2.85) and 47.8(43.6, 62.0) to 3.04 ± 0.63 and 57.2 ± 14.7, respectively. With the elimination of TR and the increase of forward blood flow of the tricuspid valve, the extravascular lung water [798.0 (673.0, 1147.0) vs. 850.3 ± 376.1, Conclusion: Invasive right atrium pressure may act as a potential candidate for TR evaluation and procedural guidance. Elimination of TR by LuX-Valve implantation improves the cardiac output and right atrium pressure and has no significant effect on the pulmonary artery pressure even with the increment of forward blood flow, suggesting the hemodynamic superiority of transcatheter tricuspid valve replacement but needs further study.

Indexed as

hemodynamicsLuX-Valvetranscatheter tricuspid valve intervention (TTVI)transcatheter tricuspid valve replacementtricuspid regurgitation

Identifiers

PMID36312292
PMCPMC9614150

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.