ArticleFrontiers in cardiovascular medicine2022
A novel and effective ECG method to differentiate right from left ventricular outflow tract arrhythmias: Angle-corrected V2S.
Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.
- Diagnostic accuracy of electrocardiogram algorithms for differentiating left from right outflow tract ventricular arrhythmia: a systematic review and network meta-analysis.Heart (British Cardiac Society) · 2026Pooled it
- Four overlooked errors in ROC analysis: how to prevent and avoid.BMJ evidence-based medicine · 2025Article
- Predictive value of surface electrocardiogram in localizing right ventricular outflow tract premature beats: a study combining intracardiac echocardiography and electroanatomical mapping under all-zero fluoroscopy ablation.Frontiers in physiology · 2025Article
- Differentiating Origins of Outflow Tract Ventricular Arrhythmias: The Correction of Transitional Zone Index Is Not Superior to the Original One.Cardiology · 2024Article
- Commentary: A novel and effective ECG method to differentiate right from left ventricular outflow tract arrhythmias: angle-corrected V2S.Frontiers in cardiovascular medicine · 2023Article
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Authors and funding
13 authors at 5 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Background and aims: Standard 12-lead electrocardiogram (ECG) patterns combined with the anatomical cardiac long-axis angle revealed by chest X-ray can prevent the influence of cardiac rotation, physical shape, and lead position, so it may be an ideal means to predict the origin of the outflow tract (OT) ventricular arrhythmias (OTVAs) for ablation procedures. The study explores the value of this strategy in identifying the origin of OTVA. Methods: This study was conducted using a retrospective cohort and a prospective cohort of consecutive patients at two centers. The anatomical cardiac long-axis angle was calculated by measuring the angle between the cardiac long-axis (a line joining the apex to the midpoint of the mitral annulus) and the horizontal plane on a chest X-ray. The V2S angle was calculated as the V2S amplitude times the angle. We ultimately enrolled 147 patients with symptomatic OTVAs who underwent successful radiofrequency catheter ablation (RFCA) (98 women (66.7%); mean age 46.9 ± 14.7 years; 126 right ventricular OT (RVOT) origins, 21 left ventricular OT (LVOT) origins) as a development cohort. The new algorithm was validated in 48 prospective patients (12 men (25.0%); mean age 48.0 ± 15.8 years; 36 RVOT, 12 LVOT origins). Results: Patients with RVOT VAs had greater V2S, long-axis angle, and V2S angle than patients with LVOT VA (all Conclusion: V2S angle can be a novel measure that can be used to accurately differentiate RVOT from LVOT origins. It could help decrease ablation duration and radiation exposure.
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