Evidence map›Paper›PMID 36311998›Full record

ArticleWorld journal of diabetes2022

Correlation between gut microbiota and glucagon-like peptide-1 in patients with gestational diabetes mellitus.

Yun-Yi Liang, Ling-Yu Liu, Yan Jia, Yi Li, Jie-Na Cai, Yi Shu, Jing-Yi Tan, Pei-Yi Chen, Hong-Wei Li, Hui-Hua Cai and 1 more

Abstract read
In one paragraph

Article in World journal of diabetes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Imbalance of gut microbiota in gestational diabetes.BMC pregnancy and childbirth · 2024
    Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. The advantages ofFuture microbiology · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Alterations in the Gut Microbiota Composition in Obesity with and without Type 2 Diabetes: A Pilot Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Article
  18. The Ketogenic Effect of SGLT-2 Inhibitors-Beneficial or Harmful?Journal of cardiovascular development and disease · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yun-Yi LiangHealth Management Center, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan 528000, Guangdong Province, China.
Ling-Yu LiuThe First Affiliated Hospital, Henan University of Chinese Medicine, Zhengzhou 450000, Henan Province, China.
Yan JiaHealth Management Center, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan 528000, Guangdong Province, China.
Yi LiHealth Management Center, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan 528000, Guangdong Province, China.
Jie-Na CaiClinical Laboratory, Puning People's Hospital, Puning 515300, Guangdong Province, China.
Yi ShuHealth Management Center, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan 528000, Guangdong Province, China.
Jing-Yi TanHealth Management Center, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan 528000, Guangdong Province, China.
Pei-Yi ChenHealth Management Center, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan 528000, Guangdong Province, China.
Hong-Wei LiInstitute of Biotherapy, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Hui-Hua CaiDepartment of Obstetrics and Gynecology, Guangdong Provincial People's Hospital, Guangzhou 510080, Guangdong Province, China.
Xiang-Sheng CaiShenzhen Hospital, University of Chinese Academy of Sciences, Shenzhen 518001, Guangdong Province, China. xiangshengcai@yeah.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGestational diabetes mellitus (GDM) places both the mother and offspring at high risk of complications. Increasing evidence suggests that the gut microbiota plays a role in the pathogenesis of GDM. However, it is still unclear whether the gut microbiota is related to blood biochemical traits, particularly glucagon-like peptide-1 (GLP-1), in GDM patients.

aimTo explore the correlation between the gut microbiota and blood biochemical traits, particularly GLP-1, in GDM patients.

methodsThe V4 region of the 16S ribosomal ribonucleic acid (rRNA) gene was sequenced based on the fecal samples of 35 pregnant women with GDM and was compared to that of 25 pregnant women with normal glucose tolerance (NGT).

resultsThe results showed that

conclusionThe results of this study reveal novel relationships between the gut microbiome, blood bio-chemical traits, particularly GLP-1, and GDM status. These findings suggest that some genera are crucial for controlling blood glucose-related indices and may be beneficial for GDM treatment. Alteration in the microbial composition of the gut may potentially serve as a marker for identifying individuals at risk of GDM.

Indexed as

Gestational diabetes mellitusGlucagon-like peptide-1GlucoseGut microbiome

Identifiers

PMID36311998
PMCPMC9606788

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.