Evidence map›Paper›PMID 36311792›Full record

ArticleFrontiers in immunology2022

A novel inflammation-related lncRNAs prognostic signature identifies LINC00346 in promoting proliferation, migration, and immune infiltration of glioma.

Wen-Jing Zeng, Lei Zhang, Hui Cao, Dongjie Li, Hao Zhang, Zhiwei Xia, Renjun Peng

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

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  6. Exosome-mediated siRNA delivery in cancer: Loading strategies, targeting approaches, and therapeutic outcomes.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Wen-Jing ZengDepartment of Pharmarcy, Xiangya Hospital, Central South University, Changsha, China.
Lei ZhangDepartment of Neurology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Science, Beijing, China.
Hui CaoDepartment of Psychiatry, The Second People's Hospital of Hunan Province, The Hospital of Hunan University of Chinese Medicine, Changsha, China.
Dongjie LiDepartment of Geriatrics, Xiangya International Medical Center, Xiangya Hospital, Central South University, Changsha, China.
Hao ZhangDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China.
Zhiwei XiaDepartment of Neurology, Hunan Aerospace Hospital, Changsha Medical University, Changsha, China.
Renjun PengDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China.
Central South University · CNChangsha Medical University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNSecond Affiliated Hospital of Hunan University of Traditional Chinese Medicine · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, a total of 13 inflammation-related lncRNAs with a high prognostic value were identified with univariate, multivariate Cox regression analysis, and LASSO analysis. LINC00346, which is one of the 13 lncRNAs identified, was positively associated with type 2 macrophage activation and the malignant degree of glioma. Fluorescence

Indexed as

GliomaRNA, Long NoncodingCell ProliferationHumansInflammationIn Situ Hybridization, FluorescencePrognosisRNA, Long NoncodinggliomainflammationlncRNAprognostictarget

Identifiers

PMID36311792
PMCPMC9609424
OpenAlexW4304957531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.