Evidence map›Paper›PMID 36311661›Full record

ArticleFrontiers in veterinary science2022

Allogeneic and xenogeneic lymphoid reconstitution in a

Renan B Sper, Jessica Proctor, Odessa Lascina, Ling Guo, Kathryn Polkoff, Tobias Kaeser, Sean Simpson, Luke Borst, Katherine Gleason, Xia Zhang and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. The making of cells and organs in xenogeneic animal bioreactor.Signal transduction and targeted therapy · 2026
    Review
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Renan B SperComparative Medicine Institute, North Carolina State University, Raleigh, NC, United States.
Jessica ProctorComparative Medicine Institute, North Carolina State University, Raleigh, NC, United States.
Odessa LascinaDepartment of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, United States.
Ling GuoComparative Medicine Institute, North Carolina State University, Raleigh, NC, United States.
Kathryn PolkoffComparative Medicine Institute, North Carolina State University, Raleigh, NC, United States.
Tobias KaeserComparative Medicine Institute, North Carolina State University, Raleigh, NC, United States.
Sean SimpsonComparative Medicine Institute, North Carolina State University, Raleigh, NC, United States.
Luke BorstComparative Medicine Institute, North Carolina State University, Raleigh, NC, United States.
Katherine GleasonComparative Medicine Institute, North Carolina State University, Raleigh, NC, United States.
Xia ZhangComparative Medicine Institute, North Carolina State University, Raleigh, NC, United States.
Bruce CollinsComparative Medicine Institute, North Carolina State University, Raleigh, NC, United States.
Yanet MurphyDepartment of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, United States.
Jeffrey L PlattDepartment of Surgery and Microbiology and Immunology, University of Michigan Health System, Ann Arbor, MI, United States.
Jorge A PiedrahitaComparative Medicine Institute, North Carolina State University, Raleigh, NC, United States.
North Carolina State University · USMichigan Medicine · US

Funding

Immunodeficient Pigs for Stem Cell­-Based Regenerative MedicineR01OD023138 · OD · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI PIEDRAHITA, JORGE A · 2017 to 2020
$1.8M
NIH HHS R01 OD023138
6 · The paper itself

Abstract

Mice with severe combined immunodeficiency are commonly used as hosts of human cells. Size, longevity, and physiology, however, limit the extent to which immunodeficient mice can model human systems. To address these limitations, we generated

Indexed as

allotransplantationhematopoieticIL2RGpigRAG2severe combined immunodeficiencytransgenicxenotransplantation

Identifiers

PMID36311661
PMCPMC9614384
OpenAlexW4306163740

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.