Evidence map›Paper›PMID 36311525›Full record

ArticleFrontiers in psychiatry2022

Long-term effect of transcranial direct current stimulation in the treatment of chronic tinnitus: A randomized, placebo-controlled trial.

Tadeas Mares, Jakub Albrecht, Jozef Buday, Gabriela Podgorna, Thai Hong Le, Eva Magyarova, Katerina Poshor, Jakub Halik, Jan Buna, Vaclav Capek and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05437185 (The Transcranial Direct Current Stimulation Treatment of Tinnitus and Its Psychiatric Comorbidities), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05437185 nacompletednot on this map

The Transcranial Direct Current Stimulation Treatment of Tinnitus and Its Psychiatric Comorbidities

TypeinterventionalSponsorCharles University, Czech RepublicRan2019 to 2022Enrolled44ConditionsTinnitusArmsTranscranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Efficacy of non-invasive neuromodulation for chronic tinnitus: a systematic review and meta-analysis of randomized controlled trials.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Review
  5. Tinnitus Rehabilitation Through Electrical Stimulation as a Neuromodulation Method: A Scoping Review.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tadeas MaresDepartment of Psychiatry, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czechia.
Jakub AlbrechtDepartment of Psychiatry, Krajska zdravotni a.s. - Most Hospital, Most, Czechia.
Jozef BudayDepartment of Psychiatry, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czechia.
Gabriela PodgornaDepartment of Psychiatry, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czechia.
Thai Hong LeDepartment of Psychiatry, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czechia.
Eva MagyarovaDepartment of Psychiatry, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czechia.
Katerina PoshorDepartment of Psychiatry, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czechia.
Jakub HalikDepartment of Psychiatry, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czechia.
Jan BunaDepartment of Psychiatry, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czechia.
Vaclav CapekDepartment of Psychiatry, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czechia.
Lenka KostylkovaNational Institute of Mental Health, Klecany, Czechia.
Johana KlasovaDepartment of Internal Medicine, First Faculty of Medicine, Charles University and Military University Hospital, Prague, Czechia.
Vratislav FabianDepartment of Physics, Faculty of Electrical Engineering, Czech Technical University in Prague, Prague, Czechia.
Martin AndersDepartment of Psychiatry, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czechia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Tinnitus is an intrusive and chronic illness affecting a significant portion of the population, decreasing affected individuals' quality of life and socioeconomic functioning. Transcranial Direct Current Stimulation (tDCS) is a non-invasive neuromodulatory method utilizing weak electrical currents to elicit short and long-term central nervous system changes. Several studies have proven its effect on tinnitus. We aimed to broaden the knowledge and provide data on the effect and its retention. Methods: In the randomized, double-blinded, sham-controlled trial, 39 patients (active Results: We reached a delayed, significant long-term improvement ( Conclusion: We proved partial, positive, long-term effects of tDCS on tinnitus and short-term, negative, transient effect on a specific aspect of the general quality of life. We expanded upon the results of previous trials and provided data concerning the longevity and the precise effect of multiple sessions, bifrontal DLPFC tDCS. Our sample size ( Clinical trial registration: [www.ClinicalTrials.gov], identifier [NCT05437185].

Indexed as

bifrontal tDCSdorsolateral prefrontal cortexneurostimulationnon-invasiveprotocol optimizationtDCStinnitustranscranial direct current stimulation (tDCS)

Identifiers

PMID36311525
PMCPMC9606613

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.