Evidence map›Paper›PMID 36311375›Full record

Review3 Biotech2022

Bioactivity profiling of the extremolyte ectoine as a promising protectant and its heterologous production.

Zhi Ma, Chutian Wu, Linjiang Zhu, Renjie Chang, Weilin Ma, Yanfeng Deng, Xiaolong Chen

Open access · greenAbstract readReview
In one paragraph

Review in 3 Biotech, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
11.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  4. Review
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  11. Microorganisms · 2025
    Article
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  16. Genomic Investigation of DesertMicroorganisms · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zhi MaCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310014 People's Republic of China.
Chutian WuCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310014 People's Republic of China.
Linjiang ZhuCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310014 People's Republic of China.
Renjie ChangCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310014 People's Republic of China.
Weilin MaCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310014 People's Republic of China.
Yanfeng DengCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310014 People's Republic of China.
Xiaolong ChenCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310014 People's Republic of China.ORCID 0000-0003-3869-352X
Zhejiang University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ectoine is a compatible solutes that is diffusely dispersed in bacteria and archaea. It plays a significant role as protectant against various external pressures, such as high temperature, high osmolarity, dryness and radiation, in cells. Ectoine can be utilized in cosmetics due to its properties of moisturizing and antiultraviolet. It can also be used in the pharmaceutical industry for treating various diseases. Therefore, strong protection of ectoine creates a high commercial value. Its current market value is approximately US$1000 kg

Indexed as

EctoineHeterogeneous productionMetabolic engineeringSkin protection

Identifiers

PMID36311375
PMCPMC9606177
OpenAlexW4307969922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.