ArticleAJOG global reports2022
Class III obesity is an independent risk factor for unsuccessful induction of labor.
Article in AJOG global reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06199154 (Induction of Labor in Morbidly Obese Patients), which is not on this map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Induction of Labor in Morbidly Obese Patients: Comparison of 50 mcg and 25 mcg Misoprostol - A Randomized Control Trial
Who cites it
11 citing papers in PubMed.
- Randomized controlled trial of traxi panniculus retractor use during non-emergent cesarean delivery.Pregnancy (Hoboken, N.J.) · 2026Article
- Oral Misoprostol +/- Double-Balloon Catheter Versus Vaginal Insertion of Dinoprostone for Induction of Labour at Full-Term.Geburtshilfe und Frauenheilkunde · 2026Article
- Cervical ripening with mechanical method vs oral misoprostol in pregnancies with elevated BMI: a cohort study.Archives of gynecology and obstetrics · 2026Article
- BMI-Stratified Risk of Cesarean Delivery Following Labor Induction: A Robson Classification-Based Cohort Study with Predictive Modeling.Journal of clinical medicine · 2026Article
- Labor Induction in Obese Pregnancies at Term: Risk Factors and Pregnancy Outcomes.Journal of pregnancy · 2026Article
- Body mass index and failed induction of labor: A cohort study.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Is indication for induction of labor associated with mode of delivery in term first births? A Norwegian registry-based study.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Prepregnancy overweight and obesity and the risk of adverse pregnancy outcomes.Scientific reports · 2025Article
- Low-dose Oral Misoprostol after Cervical Ripening with a Double-balloon Catheter: 25 µg or 50 µg?Geburtshilfe und Frauenheilkunde · 2025Article
- Association Between Pre-Pregnancy Body Mass Index and Labor Induction Success Rates: A Case Control Study.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Does Obesity Influence Women's Decision Making about the Mode of Delivery?Journal of clinical medicine · 2022Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough obesity is a known risk factor for cesarean delivery, there is a paucity of data on the course of induction of labor in these patients.
objectiveWith emerging data on the safety of 39-week inductions, we aimed to: (1) determine if Class III obesity, including morbid obesity, is an independent risk factor for nonachievement of complete dilation and vaginal delivery after induction of labor, (2) evaluate the characteristics of the induction of labor course and immediate complications, and (3) evaluate the number of induction agents necessary to be associated with vaginal deliveries. We hypothesized that as body mass index increased, it would take longer to achieve complete cervical dilation, more induction agents would be required, and there would be a higher rate of cesarean delivery. STUDY
designThis was a retrospective cohort study of singleton gestations undergoing induction of labor from 2013 to 2020 at a single center. Study groups were defined as nonobese (body mass index <30 kg/m
resultsA total of 3046 individuals met the inclusion criteria. As body mass index increased, the indications for induction were more likely to be maternal. Rate of achievement of complete dilation decreased with increasing body mass index (973 [88.5%] in the body mass index <30 group vs 455 [70.8%] in the body mass index ≥40 group; adjusted odds ratio, 0.3; 95% confidence interval, 0.2-0.4). The rate of cesarean delivery also increased (149 [13.5%] in the body mass index <30 group vs 207 [30.9%] in the body mass index ≥40 group; adjusted odds ratio, 3.2; 95% confidence interval, 2.5-4.2), as did the time to complete dilation (15.3 hours in the body mass index <30 group vs 18.8 hours in the body mass index ≥40 group;
conclusionClass III obesity is an independent risk factor for nonachievement of complete dilation and vaginal delivery following induction of labor. Furthermore, inductions in these patients require more time and are more likely to require multiple agents.
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