Evidence map›Paper›PMID 36311261›Full record

ArticleCurrent stem cell reports2018

It's Electric: When Technology Gives a Boost to Stem Cell Science.

Abraham P Lee, Mohammad Aghaamoo, Tayloria N G Adams, Lisa A Flanagan

Abstract read
In one paragraph

Article in Current stem cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Abraham P LeeDepartments of Biomedical Engineering and Mechanical & Aerospace Engineering, NSF I/UCRC, Center for Advanced Design & Manufacturing of Integrated Microfluidics (CADMIM), Biomolecular Microsystems and Nano Transducers (BioMiNT) Lab, 3120 Natural Sciences II, Irvine, CA 92697-2715, USA.
Mohammad AghaamooDepartment of Biomedical Engineering, Biomolecular Microsystems and Nano Transducers (BioMiNT) Lab, 3130 Engineering Hall, Irvine, CA 92697-2715, USA.
Tayloria N G AdamsDepartments of Biomedical Engineering and Neurology, Sue & Bill Gross Stem Cell Research Center, University of California, Irvine, 3200 Gross Hall, 845 Health Sciences Road, Irvine, CA 92697-1705, USA.
Lisa A FlanaganDepartments of Neurology, Biomedical Engineering and Anatomy & Neurobiology, Sue & Bill Gross Stem Cell Research Center, University of California, Irvine, 3030 Gross Hall, 845 Health Sciences Road, Irvine, CA 92697-1705, USA.

Funding

University of California Health Participation in the National COVID Cohort Collaborative (N3C)UL1TR001414 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, VILAIN, ERIC J. · 2015 to 2023
$35.1M
Training Program in Stem Cell Translational Medicine for Neurological DisordersT32NS082174 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI PETER John DONOVAN, Leslie Michels Thompson · 2013 to 2026
$3.3M
Integrated Microfluidic Platform for Point-of-Care SerodiagnosticsR43AI102288 · NIAID · IMMPORT THERAPEUTICS, INC. · PI LEE, ABRAHAM P, LIANG, XIAOWU · 2012 to 2013
$600k
NCATS NIH HHS UL1 TR001414NIAID NIH HHS R43 AI102288NINDS NIH HHS T32 NS082174
6 · The paper itself

Abstract

Purpose of Review: Advanced technologies can aid discoveries in stem cell science in surprising ways. The application of electrokinetic techniques, which use electric fields to interrogate or separate cells, to the study of stem cells has yielded important insights into stem cell function. These techniques probe inherent cell properties, obviating the need for cell-type specific labels. Recent Findings: Analysis of a variety of stem cell types including hematopoietic, mesenchymal and adipose-derived, neural, and pluripotent stem cells by electrokinetic techniques has revealed fate-specific signatures of cells. Distinct inherent cell properties are sufficient for their label-free enrichment without causing cell damage or toxicity. Summary: The successful application of label-free techniques to the analysis and sorting of stem cells open new avenues for exploring the basic biology of stem cells and optimizing their use in regenerative medicine applications.

Indexed as

AnalysisDielectrophoresisImpedanceMembrane capacitanceSeparationStem cell

Identifiers

PMID36311261
PMCPMC9616103

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.