Evidence map›Paper›PMID 36311247›Full record

ArticleFrontiers in physiology2022

Initial clinical validation of a hybrid

Libera Fresiello, Kavitha Muthiah, Kaatje Goetschalckx, Christopher Hayward, Maria Rocchi, Maxime Bezy, Jo P Pauls, Bart Meyns, Dirk W Donker, Krzysztof Zieliński

Abstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Technological evolution ofFrontiers in physiology · 2025
    Review
  3. Article
  4. Article
  5. AnFrontiers in physiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Libera FresielloCardiovascular and Respiratory Physiology, University of Twente, Enschede, Netherlands.
Kavitha MuthiahDepartment of Cardiology, St Vincent's Hospital, Sydney, NSW, Australia.
Kaatje GoetschalckxDepartment of Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium.
Christopher HaywardDepartment of Cardiology, St Vincent's Hospital, Sydney, NSW, Australia.
Maria RocchiDepartment of Cardiovascular Sciences, Katholieke Universiteit Leuven, Leuven, Belgium.
Maxime BezyDepartment of Cardiovascular Sciences, Katholieke Universiteit Leuven, Leuven, Belgium.
Jo P PaulsSchool of Engineering, Griffith University, Southport, QLD, Australia.
Bart MeynsDepartment of Cardiovascular Sciences, Katholieke Universiteit Leuven, Leuven, Belgium.
Dirk W DonkerCardiovascular and Respiratory Physiology, University of Twente, Enschede, Netherlands.
Krzysztof ZielińskiNalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Simulators are expected to assume a prominent role in the process of design-development and testing of cardiovascular medical devices. For this purpose, simulators should capture the complexity of human cardiorespiratory physiology in a realistic way. High fidelity simulations of pathophysiology do not only allow to test the medical device itself, but also to advance practically relevant monitoring and control features while the device acts under realistic conditions. We propose a physiologically controlled cardiorespiratory simulator developed in a mixed

Indexed as

0D modelsartificial organscardiorespiratory simulatorexercise physiologyin vitro simulatorlumped parameter modelmechanical circulatory supportventricular assist device

Identifiers

PMID36311247
PMCPMC9606213

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.