Evidence map›Paper›PMID 36311173›Full record

ReviewVirusdisease2022

Direct, indirect, post-infection damages induced by coronavirus in the human body: an overview.

Sivan Padma Priya, P M Sunil, Sudhir Varma, Carel Brigi, Mohammad Faruq Abd Rachman Isnadi, J A Jayalal, R Arunkumar Shadamarshan, S Suresh Kumar, Neela Vasantha Kumari, Rishi P R Kumar

Open access · bronzeAbstract readReview
In one paragraph

Review in Virusdisease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
  3. Inhibitory Effects ofACS omega · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 10 institutions in 5 countries.

Sivan Padma PriyaDepartment of Basic Medical Sciences, RAK College of Dental Sciences, RAK Medical and Health Sciences, Ras Al Khaimah, UAE.ORCID 0000-0002-3162-5834
P M SunilDepartment of Oral Pathology and Microbiology, Sree Anjaneya Institute of Dental Sciences, Calicut, Kerala India.
Sudhir VarmaDepartment of Clinical Sciences, College of Dentistry, Center for Medical and Bio-Allied Health Science Research, Ajman University, Ajman, UAE.
Carel BrigiMolecular Medicine and Translational Research, University of Sharjah, Sharjah, UAE.
Mohammad Faruq Abd Rachman IsnadiDepartment of Pathobiology and Medical Diagnostics, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Malaysia.
J A JayalalDepartment of Surgery, Kanyakumari Medical College and Hospital, Asaripallam, India.
R Arunkumar ShadamarshanDental Officer and Graded Specialist (Oral and Maxillofacial Surgery), Indo Bhutan Friendship Hospital, IMTRAT, Thimpu Bhutan, 11001 Bhutan.
S Suresh KumarCentre for Materials Engineering and Regenerative Medicine,, Bharath Institute of Higher Eduction and Research, Chennai, 600073 Tamil Nadu India.
Neela Vasantha KumariDepartment of Medical Microbiology and Parasitology, Universiti Putra Malaysia (UPM), Serdang, Selangor 43400 Malaysia.
Rishi P R KumarTbilisi Medical University, Tbilisi, Georgia.
Ajman University · AEBharath University · INCentre for Bhutan Studies and GNH Research · BTKanyakumari Government Medical College · INMalabar Medical College Hospital and Research Centre · INRas al-Khaimah Medical and Health Sciences University · AETbilisi State Medical University · GEUniversiti of Malaysia Sabah · MYUniversiti Putra Malaysia · MYUniversity of Sharjah · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Severe acute respiratory syndrome Coronavirus-2 invades the cells via ACE2 receptor and damages multiple organs of the human body. Understanding the pathological manifestation is mandatory to endure the rising post-infection sequel reported in patients with or without comorbidities. Materials and methods: Our descriptive review emphasises the direct, indirect and post-infection damages due to COVID-19. We have performed an electronic database search according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines with selective inclusion and exclusion criteria. Results: The included studies substantiated the extensive damages in the multiple organs due to direct and indirect consequences of COVID-19. After an apparent recovery, the prolonged presentation of the symptoms manifests as post-COVID that can be related with persisting viral antigens and dysregulated immune response. Conclusion: A few of the symptoms of respiratory, cardiovascular, and neuropsychiatric systems that persist or reappear as post-COVID manifestations. Vaccination and preventive programs will effectively reduce the prevalence but, the post-COVID, a multisystem manifestation, will be a significant tribulation to the medical profession. However, the issue can be managed by implementing public health programs, rehabilitation services, and telemedicine virtual supports to raise awareness and reduce panic.

Indexed as

COVID-19Immune dysregulationMultiple organ dysfunctionPost-COVIDPost-infection damagesSARS-CoV-2Viral pathogenesis

Identifiers

PMID36311173
PMCPMC9593972
OpenAlexW4307201678

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.