ArticleBioactive materials2023
Advances in orthodontic clear aligner materials.
Article in Bioactive materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 160 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
160 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Ageing effects on chemical, physical, mechanical, and morphological properties of clear aligners - a systematic review.Progress in orthodontics · 2026Pooled it
- Impact of Clear Aligners on the Oral Microbiome: A Systematic Review of Current Evidence.Clinical and experimental dental research · 2026Pooled it
- Assessing the environmental impact of clear aligner therapy: a scoping review.Frontiers in dental medicine · 2026Pooled it
- Sustainable clear aligner practice in esthetic and prosthetic dentistry: a scoping review for practical implementation.Frontiers in oral health · 2026Pooled it
- Root resorption caused by aligners, self-ligating appliances, and conventional fixed appliances: a CBCT-based meta-analysis.BMC oral health · 2025Pooled it
- A systematic review of biomechanics of clear aligners by finite element analysis.BMC oral health · 2025Pooled it
- The biomechanical effects of clear aligner trimline designs and extensions on orthodontic tooth movement: a systematic review.BMC oral health · 2024Pooled it
- Impact of reducing aligners' wear schedule from 7-days to 3-days on the predictability of tooth movement and treatment efficiency: a randomized controlled trial.Clinical oral investigations · 2026Trial
- Alterations in condylar position and bite force distribution following clear aligner use: a single-arm clinical trial.Clinical oral investigations · 2026Trial
- Predictability of maxillary canine retraction comparing power arm and non-power arm using 24 sets of In-house clear aligner in premolar extraction case: a randomized controlled trial.BMC oral health · 2025Trial
- Accuracy of Preliminary Maxillary Canine and Anchorage Tooth Movement in Premolar Extraction Cases Using 12 In-House Clear Aligners: A Randomised Control Trial Comparing Power Arm and Control.Orthodontics & craniofacial research · 2025Trial
- Impact of Different Cleaning Protocols on the Optical and Morphological Properties of 3D-Printed Aligners After In Vitro Aging.European journal of dentistry · 2026Article
- In Vivo Assessment of SED: A Novel Biomechanical Indicator for Periodontal Tissue Remodeling in Clear Aligner Therapy.Annals of biomedical engineering · 2026Article
- Clinical Outcomes of Sequential Distalization with Clear Aligners: A Systematic Review and Meta-Analysis.Dentistry journal · 2026Review
- Antimicrobial effect of treating thermoformable cellulose-based materials with essential oils.Clinical oral investigations · 2026Article
- Forces and Moments Generated by Thermoforming Aligners and Direct-Printed Aligners: A Systematic Review.Dentistry journal · 2026Review
- Comparative evaluation of physicochemical, mechanical, and biological properties of biodegradable poly(lactic acid) (PLA) and commercial aligner materials.Dental materials : official publication of the Academy of Dental Materials · 2026Article
- Does Thermoforming Setup Affect Thickness in Thermoplastic Orthodontic Appliances? A Comparison of Single vs. Dual-Model Fabrication.Polymers · 2026Article
- A Dual Cell-Line Molecular Platform to Assess Sub-Threshold Biocompatibility: Application to Processed Orthodontic Clears Aligners.Orthodontics & craniofacial research · 2026Article
- A DMAHDM-herbal hybrid gargle for orthodontic-associated complications via oral microbiota regulation, inflammation inhibition, and enamel protection.Materials today. Bio · 2026Article
100 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rapid technological improvements in biomaterials, computer-aided design (CAD) and manufacturing (CAM) have endorsed clear aligner therapy (CAT) as a mainstay of orthodontic treatment, and the materials employed for aligner fabrication play an all-important role in determining the clinical performance of clear aligners. This narrative review has attempted to comprehensively encompass the entire gamut of materials currently used for the fabrication of clear aligners and elucidate their characteristics that are crucial in determining their performance in an oral environment. Historical developments and current protocols in aligner fabrication, features of contemporary bioactive materials, and emerging trends related to CAT are discussed. Advances in aligner material chemistry and engineering possess the potential to bring about radical transformations in the therapeutic applications of CAT; in the absence of which, clear aligners would continue to underperform clinically, due to their inherent biomechanical constraints. Finally, while innovations in aligner materials such as shape memory polymers, direct three-dimensional (3D) printed clear aligners and bioactive materials combined with clear aligner materials are essential to further advance the applications of CAT; increased awareness of environmental responsibilities among aligner manufacturers, aligner prescribing clinicians and aligner users is essential for better alignment of our climate change goals towards a sustainable planet.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.