Evidence map›Paper›PMID 36310858›Full record

ArticleFrontiers in cellular and infection microbiology2022

Predictive value of the presence of

Xiaohui Chen, Bohong Xian, Junmin Wei, Yixiang Chen, Dongyang Yang, Xiaorong Lai, Lifang Liu, Yinghong Wu, Xiayi Lin, Yu Deng and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Intratumoral microbiota: a new force in the development and treatment of esophageal cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  7. Review
  8. Review
  9. Article
  10. Novel milestones for early esophageal carcinoma: From bench to bed.World journal of gastrointestinal oncology · 2024
    Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. The relationship betweenEpidemiology and infection · 2023
    Review
  16. The role of oral microbiota in cancer.Frontiers in microbiology · 2023
    Review
  17. Editorial: Roles of microbes in esophageal disease.Frontiers in cellular and infection microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Xiaohui ChenDepartment of General Practice, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Bohong XianDepartment of General Practice, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Junmin WeiDepartment of General Practice, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Yixiang ChenDepartment of Gastroenterology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Dongyang YangDepartment of Gastroenterology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Xiaorong LaiDepartment of Gastroenterology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Lifang LiuDepartment of General Practice, Guangdong Provincial People's Hospital, Concord Medical Center, Guangdong Academy of Medical Sciences, Guangzhou, China.
Yinghong WuDepartment of Gastroenterology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Xiayi LinDepartment of General Practice, Guangdong Provincial People's Hospital, Concord Medical Center, Guangdong Academy of Medical Sciences, Guangzhou, China.
Yu DengDepartment of General Practice, Guangdong Provincial People's Hospital, Concord Medical Center, Guangdong Academy of Medical Sciences, Guangzhou, China.
Huabin ZhangDepartment of General Practice, Guangdong Provincial People's Hospital, Concord Medical Center, Guangdong Academy of Medical Sciences, Guangzhou, China.
Wanwei LiuDepartment of General Practice, Guangdong Provincial People's Hospital, Concord Medical Center, Guangdong Academy of Medical Sciences, Guangzhou, China.
Guibin QiaoDepartment of Gastroenterology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Zijun LiDepartment of General Practice, Guangdong Provincial People's Hospital, Concord Medical Center, Guangdong Academy of Medical Sciences, Guangzhou, China.
Guangdong General Hospital · CNGuangdong Provincial People's Hospital · CNGuangdong Academy of Medical Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Imbalance of oral salivary microbiota has been linked to the pathogenesis of a variety of systemic diseases, and oral bacterial species have been shown to be useful biomarkers for systemic diseases.This study aimed to characterize the alterations of oral microbiota in patients with esophageal squamous cell carcinoma (ESCC) and to evaluate the diagnostic performance of oral microbial biomarkers for ESCC. Methods: The relative abundance of flora in saliva samples was analyzed by 16S rDNA sequencing, and differences in the species present in samples from ESCC patients and healthy controls (HCs) were identified by analyzing species diversity and performing LEfSe analysis. Receiver operating characteristic (ROC) curve analysis was applied to evaluate the diagnostic performance of the characteristic bacteria individually and in combination. Results: Differences in bacterial diversity indexes were observed for the saliva of ESCC patients versus HCs ( Conclusion: This study shows that

Indexed as

Carcinoma, Squamous CellEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaBiomarkersHumansPorphyromonas gingivalisPrevotellaSalivaBiomarkersbiomarkerdiagnostic performanceesophageal squamous cell carcinoma (ESCC)receiver operating characteristic (ROC)salivary bacteria

Identifiers

PMID36310858
PMCPMC9612942
OpenAlexW4304889633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.